{"id":"W2131766013","doi":"10.3892/ijo.2014.2707","title":"Transformation of NIH3T3 mouse fibroblast cells by MUC16 mucin (CA125) is driven by its cytoplasmic tail","year":2014,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Oncogene; Cytoplasm; Biology; Mucin; Fibroblast; Serous fluid; Ectopic expression; Transformation (genetics); Malignant transformation; Cancer research; Transfection; Cell; Cell biology; Cell culture; Cell cycle; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003335047,0.0001100503,0.0001970949,0.0001347369,0.00002864012,0.0000193908,0.0004192281,0.0001845484,0.0002794174],"category_scores_gemma":[0.0001018237,0.0001008282,0.0001298297,0.00005332457,0.00006823025,0.00002261061,0.00004930949,0.000178422,0.00002994282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007114826,"about_ca_system_score_gemma":0.0001460726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001246639,"about_ca_topic_score_gemma":0.00001679408,"domain_scores_codex":[0.9986508,0.00012903,0.0005265103,0.0001348887,0.0003999286,0.0001588124],"domain_scores_gemma":[0.9986604,0.00003993977,0.0003952742,0.0001028646,0.0007018871,0.00009967654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003404124,0.0001646304,0.0001306804,0.00001078669,0.0001050534,0.000002453166,0.0001266919,0.0002254581,0.9444523,0.00006320133,0.04585947,0.008518851],"study_design_scores_gemma":[0.001388318,0.0009848336,0.00004365021,0.00001400264,0.00000615305,0.00004940776,0.00003374564,0.0006964731,0.7013819,0.00002824239,0.2953054,0.00006787777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835359,0.0001432964,0.01021884,0.002750273,0.0002898572,0.0001320284,0.000165171,0.000003622964,0.002760988],"genre_scores_gemma":[0.9965286,0.0002990137,0.0004837789,0.0004689962,0.0001786271,0.000003938355,0.00009503185,0.0000133152,0.001928728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.249446,"threshold_uncertainty_score":0.4111654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008758482110404194,"score_gpt":0.2890968444884999,"score_spread":0.2803383623780957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}