{"id":"W2131778274","doi":"10.1371/journal.pone.0006865","title":"The Influence of Radiographic Phenotype and Smoking Status on Peripheral Blood Biomarker Patterns in Chronic Obstructive Pulmonary Disease","year":2009,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"Canadian Institutes of Health Research; British Columbia Lung Association; National Cancer Institute; National Heart, Lung, and Blood Institute; University of Pittsburgh","keywords":"Medicine; COPD; Biomarker; Airway; Pathology; Imaging biomarker; Exhaled breath condensate; Internal medicine; Asthma; Immunology; Magnetic resonance imaging; Radiology; Biology; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001218828,0.0002157992,0.0002475723,0.0004873904,0.0002058081,0.0004724199,0.0002045494,0.0003961979,0.001268496],"category_scores_gemma":[0.00499962,0.0001546769,0.0001862501,0.0004387665,0.0003313898,0.000283515,0.0002518331,0.0003772205,0.000244691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001096699,"about_ca_system_score_gemma":0.0001358462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004273425,"about_ca_topic_score_gemma":0.0005549139,"domain_scores_codex":[0.9993789,0.0003086755,0.00005149465,0.00009656501,0.00009984108,0.00006452105],"domain_scores_gemma":[0.9967577,0.001455427,0.000866713,0.0002612951,0.0002436017,0.0004153437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002880036,0.00002864995,0.9958943,0.000006650171,0.00003377023,0.00005205569,0.0000200477,0.00003433758,0.001496899,0.00001413779,0.000027616,0.002103409],"study_design_scores_gemma":[0.000004376838,0.0001282634,0.9991534,0.000002150097,0.0000196433,0.0002552366,0.00001801474,0.0001365055,0.0002092256,0.00002549438,0.00004605606,0.000001626704],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991305,0.0003326559,0.0001445625,0.00004165694,0.000004568756,0.000004058811,0.00007001565,0.000003094566,0.0002688227],"genre_scores_gemma":[0.9996676,0.000048716,0.00009934121,0.00002093142,0.000007777896,0.000003650425,0.00006719545,0.000001966918,0.00008287581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001268496,"threshold_uncertainty_score":0.006445825,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02032883188790289,"score_gpt":0.2606418620213989,"score_spread":0.2403130301334961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}