{"id":"W2131881131","doi":"10.1139/o10-160","title":"Topology models of anion exchanger 1 that incorporate the anti-parallel V-shaped motifs found in the EM structureThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.","year":2011,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of California, San Diego; University of Toronto","keywords":"Structural motif; Topology (electrical circuits); Structural similarity; Bilayer; Ion channel; Resolution (logic); Membrane protein; Similarity (geometry); Membrane topology; Band 3; Membrane; Chemistry; Computer science; Biochemistry; Mathematics; Image (mathematics); Artificial intelligence; Combinatorics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"theoretical_or_conceptual","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"medium","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"theoretical_or_conceptual","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007230951,0.0009360054,0.000947087,0.001351755,0.0002980656,0.0006868673,0.001311855,0.001075739,0.001794139],"category_scores_gemma":[0.0007138467,0.0004351236,0.0003413494,0.001129447,0.0006875055,0.001779634,0.0004564519,0.001224581,0.001618377],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00118413,"about_ca_system_score_gemma":0.0009334685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00125467,"about_ca_topic_score_gemma":0.001556512,"domain_scores_codex":[0.9998658,0.00002073403,0.0000149703,0.00003358614,0.00005274004,0.00001218366],"domain_scores_gemma":[0.9997886,0.00006582711,0.00004054926,0.00001246034,0.00007224421,0.00002035758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001265747,0.00007217602,0.0002606289,0.01068333,0.00009755128,0.0003608536,0.0001029868,0.005228543,0.008178848,0.04886319,0.03506696,0.8909584],"study_design_scores_gemma":[0.00002902643,0.0001032474,0.0003103357,0.0008933296,0.00006502174,0.0009767343,0.00003423344,0.0008904577,0.002886904,0.006420112,0.9873512,0.0000393578],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000984899,0.9882185,0.004326346,0.0007839,0.0006072201,0.00002174006,0.00006016996,0.00004832525,0.004948786],"genre_scores_gemma":[0.005382464,0.9874452,0.004056992,0.0003084643,0.0002377979,0.00003022592,0.0001287947,0.000008404656,0.002401539],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001794139,"threshold_uncertainty_score":0.008591533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04473669856156706,"score_gpt":0.2846530949445075,"score_spread":0.2399163963829404,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}