{"id":"W2131881430","doi":"10.1152/ajpcell.00034.2008","title":"PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saint Mary's University","funders":"Canadian Institutes of Health Research; University of Calgary","keywords":"Phosphorylation; Chemistry; Cell biology; Domain (mathematical analysis); Biophysics; Biochemistry; Biology; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001896617,0.0002339694,0.0002152603,0.000107031,0.000148631,0.0003034894,0.0001918035,0.000177324,0.001404699],"category_scores_gemma":[0.0002308765,0.0001336876,0.0003164801,0.00006838608,0.0002391292,0.0002323445,0.0002115638,0.000543087,0.0004738491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002828683,"about_ca_system_score_gemma":0.0001858724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000601107,"about_ca_topic_score_gemma":0.000610243,"domain_scores_codex":[0.9998404,0.00003366093,0.00001382673,0.00003875701,0.00002704556,0.00004625725],"domain_scores_gemma":[0.9998819,0.00002515835,0.00003271734,0.00001803772,0.00001057105,0.00003161366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001065192,0.00002014284,0.0001987946,0.00001419049,0.000001969402,0.00003110029,0.000007771833,0.00002465445,0.999261,0.00003064415,0.000008850169,0.0002944431],"study_design_scores_gemma":[0.0000287511,0.0001775907,0.01430947,0.000006015166,0.00001546195,0.0002337019,0.00003691182,0.001323576,0.9831663,0.00003526403,0.0006605001,0.000006524011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980236,0.00058976,0.0007074229,0.00005736591,0.00001991153,0.000009000681,0.0000601201,0.00001644056,0.0005165091],"genre_scores_gemma":[0.9984872,0.0003478173,0.0004808375,0.00002645831,0.000007603441,0.000008852328,0.00008222461,0.000009439464,0.0005496154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404699,"threshold_uncertainty_score":0.004699171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116428524032202,"score_gpt":0.2735941560274088,"score_spread":0.2624298707870867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}