{"id":"W2131899125","doi":"10.1097/01.ju.0000139539.94828.29","title":"DIHYDROTESTOSTERONE AND THE PROSTATE: THE SCIENTIFIC RATIONALE FOR 5α-REDUCTASE INHIBITORS IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA","year":2004,"lang":"en","type":"review","venue":"The Journal of Urology","topic":"Urinary Bladder and Prostate Research","field":"Medicine","cited_by":275,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Dihydrotestosterone; Medicine; Testosterone (patch); 5 Alpha-Reductase Inhibitor; Dutasteride; Hyperplasia; Lower urinary tract symptoms; Adverse effect; Androgen; Prostate; Benign prostatic hyperplasia (BPH); Prostate cancer; Endocrinology; Internal medicine; Urology; Finasteride; Hormone; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004140848,0.0002576039,0.001033077,0.0002190437,0.0003100192,0.00004975422,0.0003889495,0.0001048049,0.00001315646],"category_scores_gemma":[0.0002494266,0.00007922589,0.0002944737,0.0003736684,0.001535294,0.00005514775,0.0000428724,0.0005632441,0.000002966124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009263682,"about_ca_system_score_gemma":0.001148178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002132407,"about_ca_topic_score_gemma":0.00001933978,"domain_scores_codex":[0.9967528,0.001388397,0.0009068479,0.00017471,0.0004623908,0.0003148752],"domain_scores_gemma":[0.9955048,0.003150209,0.0006493086,0.0004451165,0.0001909991,0.00005957618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01632862,0.004126604,0.0001443858,0.01683824,0.002686112,0.0005089511,0.09903821,0.0002164316,0.0002094557,0.002274307,0.004046517,0.8535821],"study_design_scores_gemma":[0.009764167,0.01389168,0.00007224602,0.001894553,0.00430884,0.01645193,0.001572305,0.000042916,0.0000549286,0.003865288,0.947907,0.000174079],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01602976,0.9666091,0.000007216842,0.0113078,0.000192213,0.005753224,0.00006012847,0.000002054768,0.0000385733],"genre_scores_gemma":[0.02322628,0.975803,0.00004438699,0.0001001173,0.0002286762,0.000221931,0.00003857259,0.000028188,0.0003088598],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9438605,"threshold_uncertainty_score":0.5656853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05817915284011706,"score_gpt":0.3624859958050812,"score_spread":0.3043068429649641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}