{"id":"W2131914725","doi":"10.1017/s1461145701002760","title":"Effects of sigma ligands on NMDA receptor function in the bulbectomy model of depression: a behavioural study in the rat","year":2002,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Dizocilpine; NMDA receptor; Saline; Sigma receptor; Sigma-1 receptor; Locomotor activity; Psychology; Animal model; Pharmacology; Receptor; Internal medicine; Endocrinology; Chemistry; Medicine; Agonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008022993,0.0001315658,0.0001856931,0.0001055199,0.00003305011,0.00001163654,0.0009628139,0.00006634185,0.0000552975],"category_scores_gemma":[0.0001358595,0.00006474167,0.000126593,0.000137592,0.00006498177,0.000009769211,0.00007025164,0.000405891,0.000001876204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001634919,"about_ca_system_score_gemma":0.00001957901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005706467,"about_ca_topic_score_gemma":0.000004890942,"domain_scores_codex":[0.9982741,0.0005963398,0.0004245745,0.0001520052,0.0004111824,0.0001417815],"domain_scores_gemma":[0.9989481,0.0004136022,0.0003532957,0.0001294445,0.0001271752,0.00002837871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002345116,0.001613921,0.001654144,0.000005831261,0.00007045978,0.00003393215,0.0004845864,0.002053403,0.9869773,0.00002015698,0.002995407,0.001745757],"study_design_scores_gemma":[0.01351434,0.009931619,0.04202415,0.00007648466,0.0001866057,0.0001218091,0.0004470193,0.003247748,0.9287279,0.0003237555,0.001172837,0.0002256929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967289,0.0002080447,0.00007641163,0.001196318,0.00128263,0.0004193865,0.000002991939,0.000001450204,0.00008388668],"genre_scores_gemma":[0.9969704,0.0003207833,0.00001313127,0.002383811,0.0002428741,0.00003662442,0.000001316699,0.000009139882,0.00002189519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05824934,"threshold_uncertainty_score":0.2640089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02899791991507017,"score_gpt":0.3062733013428365,"score_spread":0.2772753814277664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}