{"id":"W2131914725","doi":"10.1017/s1461145701002760","title":"Effects of sigma ligands on NMDA receptor function in the bulbectomy model of depression: a behavioural study in the rat","year":2002,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Dizocilpine; NMDA receptor; Saline; Sigma receptor; Sigma-1 receptor; Locomotor activity; Psychology; Animal model; Pharmacology; Receptor; Internal medicine; Endocrinology; Chemistry; Medicine; Agonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001588563,0.0006091493,0.0006808781,0.0003349718,0.0001657616,0.0002491952,0.0002698267,0.0004092529,0.001210891],"category_scores_gemma":[0.000157251,0.0002232088,0.0003550495,0.0002391385,0.0004547182,0.0003713355,0.0002072427,0.001282023,0.0003395518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003059486,"about_ca_system_score_gemma":0.0002862192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001292226,"about_ca_topic_score_gemma":0.003196988,"domain_scores_codex":[0.9998931,0.00001847652,0.00001041971,0.00001881285,0.00002363769,0.00003571851],"domain_scores_gemma":[0.9997754,0.00002122662,0.00007075681,0.00002442407,0.00002800549,0.00008018661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001912282,0.0004221574,0.0004027006,0.00007833041,0.00002004961,0.00009081192,0.0000373582,0.00005703698,0.993335,0.00004951859,0.00003735646,0.003557366],"study_design_scores_gemma":[0.0002358983,0.02622826,0.01641868,0.00002295132,0.0001267067,0.0003713728,0.0001702789,0.0006538674,0.9544983,0.00008935224,0.001161636,0.00002273246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975744,0.001123409,0.0004997437,0.00007564425,0.00001805281,0.00002944327,0.0002035302,0.00002864325,0.0004471738],"genre_scores_gemma":[0.9916363,0.003470291,0.001413304,0.00009092061,0.00002554535,0.00009164961,0.0004371994,0.00001505864,0.002819785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001292226,"threshold_uncertainty_score":0.004050851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02899791991507017,"score_gpt":0.3062733013428365,"score_spread":0.2772753814277664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}