{"id":"W2131943340","doi":"10.1002/jps.21435","title":"The Biological Functions of Lipid Excipients and the Implications for Pharmaceutical Products Development","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Excipient; Active ingredient; Drug; Dosage form; Chemistry; Dissolution; Solubility; Solubilization; Absorption (acoustics); Chromatography; Pharmaceutical formulation; Liposome; Drug delivery; Pharmaceutical technology; Pharmacology; Organic chemistry; Materials science; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":["sts"],"category_scores_codex":[0.00611797,0.0001728467,0.000354225,0.00008127718,0.002167799,0.00004103981,0.0006795442,0.0001282571,0.00005999686],"category_scores_gemma":[0.001020772,0.00008289913,0.0001604846,0.0004583313,0.004971677,0.0001850059,0.0001370253,0.0005941818,0.00001034018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004328107,"about_ca_system_score_gemma":0.0003839448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000194828,"about_ca_topic_score_gemma":0.00000151986,"domain_scores_codex":[0.9973048,0.0007028874,0.0009340274,0.0002471739,0.0003385494,0.0004725481],"domain_scores_gemma":[0.9948831,0.003760614,0.0004523607,0.0001216794,0.0004929244,0.0002893185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01956453,0.005202284,0.2667451,0.0005388983,0.003029968,0.00003719903,0.01227193,0.00158757,0.1038498,0.1509002,0.1025061,0.3337664],"study_design_scores_gemma":[0.004167667,0.0003246158,0.0140819,0.00002133807,0.0001722122,0.0005880406,0.0004625437,0.001630723,0.01369837,0.000915495,0.9637529,0.0001841396],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9509239,0.007885537,0.001480802,0.03359139,0.003114779,0.001129643,0.00003273331,0.00002520717,0.001816044],"genre_scores_gemma":[0.9948094,0.002751741,0.000538194,0.001023838,0.0005469761,0.00005238132,0.000001165427,0.000006123462,0.000270137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8612468,"threshold_uncertainty_score":0.9991313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3559869977170428,"score_gpt":0.4775512708719158,"score_spread":0.1215642731548731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}