{"id":"W2132012375","doi":"10.1084/jem.20011883","title":"Cytokine Signaling and Hematopoietic Homeostasis Are Disrupted in <i>Lnk</i>-deficient Mice","year":2002,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; Princess Margaret Cancer Centre; University of Toronto; University Health Network; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute; Medical Research Council; Canadian Institutes of Health Research; Medical Research Council Canada","keywords":"Haematopoiesis; Cell biology; Cytokine; Biology; Stem cell factor; Myeloid; Stem cell; Progenitor cell; Lymphopoiesis; Homeostasis; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004862699,0.0001759128,0.0004958663,0.0002522753,0.00009095021,0.0000100675,0.000111732,0.00004440521,0.0009395048],"category_scores_gemma":[0.0001558469,0.0001007953,0.00007840773,0.0002960199,0.0001934014,0.00009256869,0.00004045179,0.0004016052,0.000008124741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001050799,"about_ca_system_score_gemma":0.00001254311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005848434,"about_ca_topic_score_gemma":0.0000036824,"domain_scores_codex":[0.9984932,0.00008004959,0.0006714435,0.0001206307,0.0004241928,0.0002104989],"domain_scores_gemma":[0.9989709,0.0002224115,0.0003672134,0.0001703355,0.0001019651,0.0001672098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003770416,0.0005208235,0.00125203,0.00003968828,0.00006228555,0.0002128502,0.008396111,0.00002450735,0.986015,0.00003938208,0.002437919,0.0006223708],"study_design_scores_gemma":[0.009034428,0.004670064,0.002818324,0.004226214,0.0004129994,0.01116203,0.05043272,0.0009969337,0.9115741,0.00005763936,0.00432742,0.0002871036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9696802,0.02283416,0.00006945632,0.006121526,0.0002662273,0.0001867989,0.000003034464,0.00001106122,0.0008275633],"genre_scores_gemma":[0.9977586,0.0006859885,0.0001290327,0.0009878444,0.000336012,0.000003224404,0.000001428991,0.00002054358,0.00007727217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07444087,"threshold_uncertainty_score":0.9999738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03860261836069298,"score_gpt":0.2968938334938816,"score_spread":0.2582912151331886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}