{"id":"W2132079297","doi":"10.1136/ard.2010.146043","title":"Changes in patient characteristics in anti-tumour necrosis factor clinical trials for rheumatoid arthritis: results of an analysis of the literature over the past 16 years","year":2011,"lang":"en","type":"review","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Methotrexate; Rheumatoid arthritis; Internal medicine; Clinical endpoint; Clinical trial; Physical therapy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.005279796,0.0006623088,0.004683292,0.002980982,0.0001792697,0.00137554,0.0009004849,0.0008475528,0.001622088],"category_scores_gemma":[0.01526025,0.0003814003,0.003034525,0.006319118,0.0004897404,0.001168933,0.0005074298,0.0007961523,0.0001650684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001211799,"about_ca_system_score_gemma":0.00155225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00115328,"about_ca_topic_score_gemma":0.003398705,"domain_scores_codex":[0.996106,0.0008421644,0.001552282,0.0004875675,0.0009231601,0.00008892875],"domain_scores_gemma":[0.9809766,0.01294245,0.004800621,0.0001529347,0.0009276859,0.000199706],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.004979745,0.0001624559,0.01334652,0.2806132,0.01870893,0.0003274973,0.0002281166,0.0007319119,0.0009446872,0.0003564373,0.006764629,0.6728359],"study_design_scores_gemma":[0.005980488,0.005666692,0.2773057,0.2482861,0.2024931,0.01017534,0.001265268,0.001378442,0.002910565,0.00169497,0.2424867,0.0003566165],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001331665,0.9983612,0.00003128829,0.00007328508,0.00003200199,0.000008315783,0.00007859022,0.000001636704,0.00008196355],"genre_scores_gemma":[0.01832546,0.9808173,0.0002712939,0.0002360745,0.00009600336,0.00003076691,0.0001655027,0.000002351135,0.00005520533],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9953167,"threshold_uncertainty_score":0.02792257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1517822591814825,"score_gpt":0.4218754189955652,"score_spread":0.2700931598140827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}