{"id":"W2132098257","doi":"10.1016/j.celrep.2014.07.027","title":"Perturbation of NCOA6 Leads to Dilated Cardiomyopathy","year":2014,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ministry of Education, Science and Technology; National Institute of Diabetes and Digestive and Kidney Diseases; National Research Foundation of Korea; Ministry of Agriculture, Food and Rural Affairs; Ministry of Food and Drug Safety; Ministry of Health and Welfare; National Research Foundation","keywords":"Dilated cardiomyopathy; Nonsynonymous substitution; Coactivator; Heart failure; Cardiomyopathy; Internal medicine; Biology; Peroxisome proliferator-activated receptor; Endocrinology; Medicine; Cardiology; Receptor; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003966149,0.0001177247,0.0004226494,0.00009819088,0.00004390414,0.000005705579,0.00002549198,0.00006442332,0.00002085749],"category_scores_gemma":[0.0003040238,0.0001001659,0.0001722558,0.0001984639,0.00003844656,0.0000287852,0.0000486593,0.00007422494,0.00001795239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003488383,"about_ca_system_score_gemma":0.00003970495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002294603,"about_ca_topic_score_gemma":0.000001326148,"domain_scores_codex":[0.998937,0.0000273942,0.0003533847,0.0002553108,0.0002629382,0.0001639627],"domain_scores_gemma":[0.9990581,0.00003892034,0.0001332018,0.0004456908,0.000209344,0.0001147087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003407892,0.0003319328,0.3999389,0.0007703541,0.0002010315,0.00153529,0.004001068,0.0002623906,0.5263438,0.0002326613,0.03778796,0.02825387],"study_design_scores_gemma":[0.00108029,0.0009397119,0.3003055,0.0002720492,0.0006386908,0.001436677,0.0003096811,0.00006775339,0.4102168,0.0003362269,0.2839586,0.000437932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8920029,0.0004283024,0.0009310981,0.0001761204,0.0005431699,0.000272022,0.000001147406,0.00005948524,0.1055857],"genre_scores_gemma":[0.9936352,0.00002619512,0.0003270192,0.0002142778,0.0002372817,0.00001679421,0.00001402329,0.00001744734,0.005511803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2461707,"threshold_uncertainty_score":0.4084648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014285853987021,"score_gpt":0.2402796878193284,"score_spread":0.2301368292794582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}