{"id":"W2132098257","doi":"10.1016/j.celrep.2014.07.027","title":"Perturbation of NCOA6 Leads to Dilated Cardiomyopathy","year":2014,"lang":"en","type":"article","venue":"Cell Reports","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ministry of Education, Science and Technology; National Institute of Diabetes and Digestive and Kidney Diseases; National Research Foundation of Korea; Ministry of Agriculture, Food and Rural Affairs; Ministry of Food and Drug Safety; Ministry of Health and Welfare; National Research Foundation","keywords":"Dilated cardiomyopathy; Nonsynonymous substitution; Coactivator; Heart failure; Cardiomyopathy; Internal medicine; Biology; Peroxisome proliferator-activated receptor; Endocrinology; Medicine; Cardiology; Receptor; Genetics; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001560599,0.0002974782,0.000209512,0.0003350516,0.000198174,0.000122602,0.000165808,0.0003034709,0.00108937],"category_scores_gemma":[0.0002256985,0.0001059235,0.0002378819,0.0001532324,0.0002216346,0.00007461163,0.0002191874,0.0003101903,0.0002926158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001694363,"about_ca_system_score_gemma":0.0001076286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005206232,"about_ca_topic_score_gemma":0.0008452631,"domain_scores_codex":[0.9998083,0.00003271403,0.00002380879,0.0000516175,0.00004816642,0.00003545917],"domain_scores_gemma":[0.9998412,0.00004413548,0.00002889307,0.00002101677,0.00001145434,0.00005331026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001293158,0.00005909273,0.001494768,0.00002391667,0.00001277957,0.0005448032,0.00002462945,0.00006656328,0.9955742,0.0001019906,0.0001288477,0.001839015],"study_design_scores_gemma":[0.0001246466,0.001239529,0.08566507,0.00003298274,0.0000981336,0.008687044,0.0001225376,0.004065685,0.8920591,0.0002426815,0.007644115,0.00001847635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954998,0.0006606422,0.001849846,0.0000728412,0.00004362075,0.00002549318,0.0003398031,0.00006028896,0.001447553],"genre_scores_gemma":[0.9967636,0.0004724135,0.001118823,0.00008007584,0.000009552811,0.00002517138,0.0004485739,0.00001929456,0.001062463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00108937,"threshold_uncertainty_score":0.003644288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014285853987021,"score_gpt":0.2402796878193284,"score_spread":0.2301368292794582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}