{"id":"W2132185700","doi":"10.1002/pd.1819","title":"False‐positive prenatal diagnosis of trisomy 18 by interphase FISH: Hybridization of chromosome 18 alpha‐satellite DNA probe (D18Z1) to the heterochromatic region of chromosome 9","year":2007,"lang":"en","type":"letter","venue":"Prenatal Diagnosis","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Trisomy; Heterochromatin; Hybridization probe; Satellite DNA; Aneuploidy; Chromosome 21; Interphase; Cytogenetics; Chromosome; Prenatal diagnosis; Fluorescence in situ hybridization; Fish <Actinopterygii>; Biology; Karyotype; Genetics; Molecular biology; DNA; Fetus; Gene; Pregnancy; Fishery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003240717,0.0007493722,0.001045828,0.0003294376,0.0001221777,0.00005898459,0.001071104,0.0008037248,0.0001871127],"category_scores_gemma":[0.0003415778,0.0006527084,0.0005852977,0.0004530627,0.0004478853,0.00004986121,0.0005770397,0.0004793593,0.00001143051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001126371,"about_ca_system_score_gemma":0.0001499179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002763081,"about_ca_topic_score_gemma":0.00005389035,"domain_scores_codex":[0.9958118,0.0003401972,0.001598078,0.0009452926,0.0006548326,0.0006497618],"domain_scores_gemma":[0.9964222,0.0003722008,0.001374731,0.001146803,0.0005418707,0.0001422485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005704832,0.00206132,0.008824729,0.007488183,0.002688769,0.0001842367,0.002571512,0.0001456047,0.05519414,0.00004843132,0.9124758,0.007746767],"study_design_scores_gemma":[0.000980606,0.00133328,0.0006457868,0.001745695,0.0003893746,0.00009399149,0.00009495125,0.00001533544,0.9392435,0.00004496539,0.05474167,0.000670831],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9493288,0.007188795,0.003539269,0.02006224,0.0007524402,0.004115732,0.01454165,0.00004996125,0.0004211306],"genre_scores_gemma":[0.9730846,0.003007709,0.0003530154,0.0118313,0.0008584925,0.001284679,0.009027656,0.0001454163,0.0004070944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8840494,"threshold_uncertainty_score":0.9995924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360864785389421,"score_gpt":0.2394598786504222,"score_spread":0.225851230796528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}