{"id":"W2132242617","doi":"10.1083/jcb.200601036","title":"The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER","year":2006,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":341,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Peroxisome; Endoplasmic reticulum; Biology; Cell biology; Biogenesis; Organelle; Organelle biogenesis; Mutant; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002317717,0.0003947105,0.000362897,0.0002264229,0.0002229854,0.0006045544,0.0002746835,0.0004155338,0.001251575],"category_scores_gemma":[0.0001904008,0.0003123132,0.0003730168,0.0001547291,0.0003299051,0.0008476635,0.0005473382,0.001061757,0.001732193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003805294,"about_ca_system_score_gemma":0.0002926493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000237414,"about_ca_topic_score_gemma":0.0004844019,"domain_scores_codex":[0.9998736,0.000009516319,0.00001450205,0.00004541839,0.00003559047,0.00002120141],"domain_scores_gemma":[0.999693,0.00004227153,0.00008609783,0.00006527846,0.00004072349,0.00007264331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004942946,0.000006532636,0.0001313659,0.00002039212,0.000002099741,0.00005665969,0.000007630945,0.00002358146,0.9989113,0.000153902,0.00001173123,0.0006253778],"study_design_scores_gemma":[0.0000139222,0.00004990516,0.004810296,0.000007011632,0.000005816074,0.0004671444,0.00002055234,0.0004126907,0.9909469,0.0001103519,0.003150356,0.000005091841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737191,0.002703819,0.01941666,0.0003124705,0.00006842596,0.00005175951,0.000544186,0.000280034,0.002903625],"genre_scores_gemma":[0.9514737,0.003392263,0.02495641,0.0001197458,0.00003683917,0.0000765384,0.002580686,0.0001645643,0.01719921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251575,"threshold_uncertainty_score":0.004186928,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006876098675678221,"score_gpt":0.2183991026797492,"score_spread":0.211523004004071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}