{"id":"W2132262344","doi":"10.1128/jvi.00793-10","title":"Efficacious Early Antiviral Activity of HIV Gag- and Pol-Specific HLA-B*2705-Restricted CD8 <sup>+</sup> T Cells","year":2010,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Wellcome Trust","keywords":"Biology; Epitope; Virology; CD8; Cytotoxic T cell; Immune system; HIV Antigens; T cell; Peripheral blood mononuclear cell; Viral replication; Human leukocyte antigen; Immunology; Antigen; Virus; In vitro; Viral disease; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003283441,0.000205774,0.0005909947,0.0003359228,0.0001233497,0.00001435428,0.0002689861,0.0004190793,0.0003943967],"category_scores_gemma":[0.00009148946,0.0001561814,0.0001647738,0.0001391987,0.0006385365,0.0001265308,0.00009712591,0.001216776,0.0002790742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002426804,"about_ca_system_score_gemma":0.0001136841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004865904,"about_ca_topic_score_gemma":0.00001515845,"domain_scores_codex":[0.9983293,0.0004170976,0.0004481606,0.000225832,0.00008673123,0.0004928834],"domain_scores_gemma":[0.9986876,0.0004255735,0.0003781031,0.0002695152,0.0001493735,0.00008983142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001550398,0.0006278367,0.01164648,0.000009044469,0.0003425225,0.0001840363,0.000346068,0.000008198372,0.9726084,0.00008629366,0.002732201,0.009858543],"study_design_scores_gemma":[0.01041287,0.005964951,0.3400088,0.00002469093,0.0001581301,0.001531071,0.0001100775,0.00002384257,0.6004367,0.0001823543,0.04084087,0.0003056345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997386,0.0009996785,0.0000846291,0.0005818286,0.0003535677,0.000156158,0.00008829156,0.00001243096,0.0003374548],"genre_scores_gemma":[0.998804,0.0004663781,0.0001829724,0.00002895417,0.00009445261,0.000002545961,0.0000101769,0.00001636112,0.0003941366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3721717,"threshold_uncertainty_score":0.6368893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009395206945372069,"score_gpt":0.2405632435451567,"score_spread":0.2311680365997846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}