{"id":"W2132278102","doi":"10.1152/ajpcell.00124.2012","title":"Adaptor protein 1 complexes regulate intracellular trafficking of the kidney anion exchanger 1 in epithelial cells","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Intercalated Cell; Endosome; Signal transducing adaptor protein; Biology; Cell biology; HEK 293 cells; Immunoprecipitation; Transport protein; Cytosol; Renal sodium reabsorption; Epithelial polarity; Molecular biology; Intracellular; Kidney; Chemistry; Reabsorption; Biochemistry; Signal transduction; Membrane; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003205999,0.0002243302,0.0005056792,0.00009636459,0.00005726602,0.000002841318,0.0003611626,0.0001444401,0.00003258144],"category_scores_gemma":[0.00002230717,0.0001621553,0.0002679024,0.0002127573,0.000575588,0.00001661238,0.00006679766,0.0002486258,0.000002701788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002229769,"about_ca_system_score_gemma":0.00009854719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002708855,"about_ca_topic_score_gemma":0.000004001705,"domain_scores_codex":[0.9982696,0.0003718229,0.0005753568,0.000225266,0.0001443275,0.0004135853],"domain_scores_gemma":[0.9985116,0.00002222748,0.0009051067,0.0003082273,0.0001317348,0.0001211237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005452937,0.0002711717,0.0002019706,0.00003894362,0.00004487382,4.134469e-7,0.0002908282,0.000909912,0.9970325,0.00003441855,0.0002064475,0.0004232566],"study_design_scores_gemma":[0.0007309092,0.0007682521,0.03285298,0.000043776,0.000027519,0.00000911007,0.0002735648,0.00005197708,0.9623269,0.0001453344,0.002596891,0.000172816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987542,0.0002512407,0.000144121,0.0001469639,0.0004525484,0.0002011092,0.00002184202,0.000003898368,0.00002410152],"genre_scores_gemma":[0.9984646,0.00006791469,0.0003346104,0.0001710113,0.0008144296,0.000007493446,0.00004905102,0.00002752292,0.00006336563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0347056,"threshold_uncertainty_score":0.6612501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006969153097354651,"score_gpt":0.2085347348842899,"score_spread":0.2015655817869352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}