{"id":"W2132319659","doi":"10.1074/mcp.m110.007252","title":"Uncovering the Proteome Response of the Master Circadian Clock to Light Using an AutoProteome System","year":2011,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Proteome; Suprachiasmatic nucleus; Proteomics; Circadian rhythm; Chemistry; Circadian clock; Biology; Cell biology; Biochemistry; Computational biology; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002467929,0.0004145939,0.0003632072,0.000791257,0.0002256262,0.000421418,0.0002693936,0.0003216042,0.0006374803],"category_scores_gemma":[0.0001679875,0.0001882228,0.000423311,0.0003832611,0.0001784958,0.0004988389,0.0004736333,0.0004166648,0.0003187079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002021431,"about_ca_system_score_gemma":0.0002518419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004559022,"about_ca_topic_score_gemma":0.0007871355,"domain_scores_codex":[0.9998517,0.00001334447,0.000007526412,0.00006416692,0.00004517562,0.00001805417],"domain_scores_gemma":[0.9998983,0.00001663547,0.00003134848,0.00001114779,0.00002206987,0.0000205316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006033096,0.00001495625,0.002086641,0.00005917726,0.00002697342,0.00004251304,0.00001865625,0.0001264457,0.9930177,0.0001065795,0.00008651651,0.004353467],"study_design_scores_gemma":[0.00003275368,0.0003970377,0.1805032,0.00003757785,0.0001864474,0.001400767,0.0001330939,0.03536463,0.7724888,0.001065579,0.008331953,0.00005814308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9400437,0.002785476,0.0524808,0.0001751235,0.00005094286,0.00007141101,0.002879824,0.0005649192,0.0009476997],"genre_scores_gemma":[0.8751202,0.003790757,0.1109378,0.0003860741,0.00008728629,0.0001815442,0.007406916,0.0001627666,0.001926761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000791257,"threshold_uncertainty_score":0.002132535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03939383931234376,"score_gpt":0.2239631231208226,"score_spread":0.1845692838084788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}