{"id":"W2132323473","doi":"10.1677/erc-09-0004","title":"Antizyme is necessary for conversion of pancreatic tumor cells into glucagon-producing differentiated cells","year":2009,"lang":"en","type":"article","venue":"Endocrine Related Cancer","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Public Health Agency of Canada","keywords":"Glucagon; Transfection; Cell culture; Pancreas; Biology; Ornithine decarboxylase antizyme; Cell; Molecular biology; Internal medicine; Chemistry; Ornithine decarboxylase; Insulin; Cell biology; Endocrinology; Biochemistry; Enzyme; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009312335,0.0002525904,0.0006478204,0.0001816468,0.00008241948,0.00001103892,0.00009171459,0.00007240394,0.001386948],"category_scores_gemma":[0.00007320303,0.0002110833,0.0001990169,0.0003672241,0.00005941877,0.00009366167,0.00002236134,0.0001963454,0.00004144928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001169224,"about_ca_system_score_gemma":0.0001299345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003439367,"about_ca_topic_score_gemma":0.00000102753,"domain_scores_codex":[0.9983968,0.00003546952,0.0005100898,0.0004232043,0.0002511181,0.0003833114],"domain_scores_gemma":[0.9989035,0.0001155528,0.0002375242,0.0003818522,0.000191659,0.0001698809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00051331,0.0002433779,0.004326558,0.0006476547,0.0002926404,0.00002152652,0.0004141076,0.00004444047,0.9647674,0.00003166261,0.02688066,0.001816691],"study_design_scores_gemma":[0.004834553,0.0005598238,0.005061129,0.0005809901,0.0006604812,0.00001140684,0.0001191399,0.002023809,0.9799063,0.0001598113,0.005867903,0.0002146528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928606,0.003101027,0.00008066526,0.00126267,0.0007119138,0.0006887331,0.0000426175,0.0001222907,0.001129509],"genre_scores_gemma":[0.9918101,0.0009654532,0.0005578219,0.001259759,0.0001347844,0.00003294986,0.00007863365,0.00003374526,0.005126714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02101276,"threshold_uncertainty_score":0.9995259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01041442938834292,"score_gpt":0.2701999132264287,"score_spread":0.2597854838380858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}