{"id":"W2132343618","doi":"10.1111/cge.12324","title":"Evidence‐based genetic counselling implications for Huntington disease intermediate allele predictive test results","year":2013,"lang":"en","type":"review","venue":"Clinical Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Predictive testing; Genetic counseling; Allele; Disease; Trinucleotide repeat expansion; Genetic testing; Genetics; Huntington's disease; Haplotype; Germline; Biology; Medicine; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001622004,0.0007234304,0.001372241,0.002738921,0.0003013311,0.001065099,0.001199721,0.001927668,0.004124791],"category_scores_gemma":[0.005521069,0.0002399333,0.0006697704,0.00215661,0.0006703694,0.001142915,0.0007804489,0.0019603,0.001563457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001101378,"about_ca_system_score_gemma":0.001850883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002375076,"about_ca_topic_score_gemma":0.003871834,"domain_scores_codex":[0.9992926,0.0002409035,0.0001286247,0.00007433997,0.0002340973,0.00002941152],"domain_scores_gemma":[0.9966931,0.002477187,0.0002319503,0.000037026,0.000483896,0.00007673143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00003447682,0.00002792671,0.0002634381,0.0212276,0.0001008032,0.0006104168,0.00009078662,0.0002369464,0.0002599076,0.003186941,0.02878779,0.945173],"study_design_scores_gemma":[0.00003131477,0.00005138422,0.002289298,0.05043058,0.000477725,0.008157364,0.0002589886,0.0001617611,0.0003132166,0.00626718,0.9315137,0.00004747304],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008149262,0.9972295,0.0001864481,0.0009852307,0.0001716165,0.000005285545,0.0000191743,0.000007198583,0.001314145],"genre_scores_gemma":[0.001030342,0.9977548,0.0003832521,0.0004054577,0.0001538383,0.000007086372,0.00002869006,0.000002085584,0.0002345536],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004124791,"threshold_uncertainty_score":0.01379877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3693559815897948,"score_gpt":0.4629159445009974,"score_spread":0.09355996291120267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}