{"id":"W2132360332","doi":"10.1097/mcp.0b013e3282efbc56","title":"New pulmonary therapies for cystic fibrosis","year":2007,"lang":"en","type":"review","venue":"Current Opinion in Pulmonary Medicine","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Cystic fibrosis; Medicine; Cystic fibrosis transmembrane conductance regulator; Regulator; Clinical trial; Pharmacotherapy; Genetic enhancement; Intensive care medicine; Chloride channel; Bioinformatics; Internal medicine; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001418399,0.001153487,0.004054504,0.001909523,0.000130182,0.00002560711,0.0006768774,0.0005308554,0.0006314209],"category_scores_gemma":[0.001492545,0.0008311752,0.0007810647,0.001760867,0.000434215,0.0001948643,0.0002129614,0.001501184,0.0001124846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006610901,"about_ca_system_score_gemma":0.001218503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005273069,"about_ca_topic_score_gemma":0.00000168339,"domain_scores_codex":[0.9934537,0.000238382,0.002227652,0.001393757,0.001391269,0.001295208],"domain_scores_gemma":[0.9941175,0.003027765,0.0006039034,0.001117918,0.0002384374,0.0008944637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004971002,0.000288865,0.00005855116,0.1022905,0.0001062763,0.00004807325,0.00005151733,4.807643e-7,0.00000809975,0.0001814494,0.02345177,0.8730173],"study_design_scores_gemma":[0.001185505,0.0007744779,0.0001810954,0.1609656,0.0004083008,0.0006548097,0.00007228684,0.00008256333,4.78126e-7,0.0005024763,0.8346223,0.0005501523],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[4.132565e-7,0.9804933,0.003944267,0.0005886285,0.008622061,0.00530671,0.0001735217,0.0001526335,0.0007184349],"genre_scores_gemma":[0.000004174761,0.9815249,0.00351966,0.00002750438,0.008470864,0.0008093971,0.004044207,0.0002160253,0.001383277],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8724672,"threshold_uncertainty_score":0.9994139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1602030392562364,"score_gpt":0.4680765322905417,"score_spread":0.3078734930343052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}