{"id":"W2132364830","doi":"10.1200/jco.2014.57.6926","title":"Treatment-Associated Musculoskeletal and Vasomotor Symptoms and Relapse-Free Survival in the NCIC CTG MA.27 Adjuvant Breast Cancer Aromatase Inhibitor Trial","year":2014,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cancer Care Ontario","funders":"National Cancer Institute; Pfizer","keywords":"Medicine; Anastrozole; Exemestane; Vasomotor; Aromatase inhibitor; Breast cancer; Internal medicine; Adverse effect; Common Terminology Criteria for Adverse Events; Tamoxifen; Cancer; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001443683,0.0003314217,0.0008664883,0.0001591577,0.0001692148,0.0004168725,0.0004234718,0.000510757,0.002027502],"category_scores_gemma":[0.002004195,0.0001152272,0.0008786035,0.0002346149,0.000326517,0.0001873555,0.0001944631,0.001066827,0.000215626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005270239,"about_ca_system_score_gemma":0.0009525461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001441729,"about_ca_topic_score_gemma":0.003558359,"domain_scores_codex":[0.999339,0.0004593076,0.00003429071,0.00005546405,0.00006007747,0.0000518201],"domain_scores_gemma":[0.9990478,0.0003111014,0.0003548033,0.00005029088,0.0000498354,0.0001862503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.823805,0.003106249,0.08846851,0.001873099,0.005068835,0.00014183,0.0000929813,0.002855357,0.003679915,0.0005742379,0.009436268,0.06089759],"study_design_scores_gemma":[0.4977388,0.1212802,0.3489067,0.000721666,0.01082024,0.0006714051,0.0001157788,0.006553543,0.002241748,0.0008708765,0.01001206,0.00006703928],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858641,0.008791759,0.0001293266,0.0008896632,0.00008168346,0.0003681943,0.001194944,0.00001770924,0.00266264],"genre_scores_gemma":[0.9950358,0.00135099,0.0002001316,0.0005115709,0.0001891907,0.0005231205,0.001201673,0.000004008475,0.0009835289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002027502,"threshold_uncertainty_score":0.007634997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02097737467456347,"score_gpt":0.3624859293299106,"score_spread":0.3415085546553471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}