{"id":"W2132367212","doi":"10.1016/s2214-109x(14)70347-x","title":"Safety and efficacy of alternative antibiotic regimens compared with 7 day injectable procaine benzylpenicillin and gentamicin for outpatient treatment of neonates and young infants with clinical signs of severe infection when referral is not possible: a randomised, open-label, equivalence trial","year":2015,"lang":"en","type":"article","venue":"The Lancet Global Health","topic":"Antibiotic Use and Resistance","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"LIFE programme; Johns Hopkins Bloomberg School of Public Health; Medical Research Council; Bill and Melinda Gates Foundation; United States Agency for International Development","keywords":"Medicine; Gentamicin; Regimen; Antibiotics; Benzylpenicillin; Amoxicillin; Ceftriaxone; Pediatrics; Surgery; Internal medicine; Penicillin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008375722,0.0001747781,0.001016594,0.00002492952,0.0001118155,0.000009840687,0.0001224612,0.00009246408,0.00000181454],"category_scores_gemma":[0.00006651993,0.00009545965,0.0000224314,0.00009386076,0.0005126326,0.00007661262,0.00007777534,0.00008686636,2.150667e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007386015,"about_ca_system_score_gemma":0.0002954852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003221457,"about_ca_topic_score_gemma":0.00106398,"domain_scores_codex":[0.9984218,0.0003808614,0.0005724966,0.0002954252,0.00006854701,0.0002608327],"domain_scores_gemma":[0.9986003,0.0003066581,0.0006735616,0.000220426,0.0001472767,0.00005179027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8842468,0.001570172,0.09651829,0.0004266085,0.001118906,0.000001616268,0.007541152,0.00004603544,0.0006261255,0.0007487733,0.000456735,0.006698795],"study_design_scores_gemma":[0.8274325,0.07489493,0.08738252,0.001551059,0.0005340172,0.00009950274,0.001010734,0.0003035481,0.005787531,0.0003217625,0.000332096,0.0003498015],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933111,0.002604373,0.0003055207,0.0004211232,0.0001210846,0.002726659,0.0004224122,0.000008212309,0.00007953277],"genre_scores_gemma":[0.9963992,0.002771307,0.0005464167,0.0001137046,0.00002719239,0.000005280631,0.00004116067,0.000007659381,0.00008809186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07332475,"threshold_uncertainty_score":0.4869901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1018560472248068,"score_gpt":0.3812658618586596,"score_spread":0.2794098146338527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}