{"id":"W2132367212","doi":"10.1016/s2214-109x(14)70347-x","title":"Safety and efficacy of alternative antibiotic regimens compared with 7 day injectable procaine benzylpenicillin and gentamicin for outpatient treatment of neonates and young infants with clinical signs of severe infection when referral is not possible: a randomised, open-label, equivalence trial","year":2015,"lang":"en","type":"article","venue":"The Lancet Global Health","topic":"Antibiotic Use and Resistance","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"LIFE programme; Johns Hopkins Bloomberg School of Public Health; Medical Research Council; Bill and Melinda Gates Foundation; United States Agency for International Development","keywords":"Medicine; Gentamicin; Regimen; Antibiotics; Benzylpenicillin; Amoxicillin; Ceftriaxone; Pediatrics; Surgery; Internal medicine; Penicillin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003253094,0.001620093,0.004468043,0.0006972084,0.0004403747,0.001139355,0.001709808,0.003391433,0.004660933],"category_scores_gemma":[0.006577154,0.0008977186,0.001867362,0.0005417546,0.00196993,0.001690328,0.0006809345,0.002568045,0.0006754652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001182552,"about_ca_system_score_gemma":0.001267252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008105163,"about_ca_topic_score_gemma":0.001100482,"domain_scores_codex":[0.9963811,0.002470768,0.0002730695,0.0004069482,0.0002320277,0.000236223],"domain_scores_gemma":[0.995151,0.002035258,0.001171924,0.0003601748,0.0003098841,0.0009716557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9797243,0.009981122,0.0002575276,0.0004465893,0.0003112144,0.00002968508,0.00004998318,0.0001473166,0.001222619,0.0000569461,0.0001004384,0.007672267],"study_design_scores_gemma":[0.8449071,0.1533998,0.0007109122,0.00003817519,0.0001820886,0.00001894051,0.00002138281,0.0002620058,0.0002200189,0.0000861213,0.0001406863,0.00001282594],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992857,0.001828604,0.0004529318,0.0002296179,0.0003635472,0.003407097,0.000225205,0.00003417929,0.0006016964],"genre_scores_gemma":[0.9886919,0.001334215,0.002021224,0.000399564,0.0004380044,0.00595628,0.0002439714,0.00001097444,0.0009038766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004660933,"threshold_uncertainty_score":0.01720417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1018560472248068,"score_gpt":0.3812658618586596,"score_spread":0.2794098146338527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}