{"id":"W2132452208","doi":"10.1091/mbc.e11-12-1018","title":"GARP regulates the bioavailability and activation of TGFβ","year":2012,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":179,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; GlaxoSmithKline; University of California, San Francisco; York University; Helsingin Yliopisto","keywords":"Biology; Transforming growth factor; Cell biology; Secretion; Glycoprotein; Disulfide bond; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004354994,0.00007487754,0.0001577911,0.00003775742,0.00003728892,0.000001491343,0.0001438265,0.00009492807,0.00006716952],"category_scores_gemma":[0.0002405036,0.00003832704,0.00008265473,0.0001366917,0.0005888616,0.00001225823,0.0001785351,0.0001310547,0.000004609172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001465693,"about_ca_system_score_gemma":0.0000305087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004002984,"about_ca_topic_score_gemma":5.458069e-7,"domain_scores_codex":[0.999202,0.0002242379,0.0001677516,0.0001193253,0.0001195861,0.0001671161],"domain_scores_gemma":[0.9991691,0.0001219868,0.00009820912,0.0004848779,0.00007951894,0.00004635305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005657365,0.0000899837,0.03579394,0.00006271551,0.00002044005,1.850577e-7,0.00008337624,9.418325e-7,0.9627366,0.0001979621,0.000146227,0.0008110662],"study_design_scores_gemma":[0.0002702888,0.0001003879,0.05641146,0.00001371071,0.00002933538,0.000005367658,0.00004453972,0.00002396463,0.941328,0.0003592282,0.001380726,0.00003301777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952505,0.00113158,0.0001476902,0.001585557,0.00003994903,0.0003054717,0.000002503908,0.000005007642,0.001531725],"genre_scores_gemma":[0.9990367,0.00003506648,0.0003400229,0.0001572094,0.00001551545,0.000004400902,0.00000457316,0.000007815617,0.0003986939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02140862,"threshold_uncertainty_score":0.2169685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01548154582648108,"score_gpt":0.2892139471282987,"score_spread":0.2737324013018176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}