{"id":"W2132492551","doi":"10.1093/jac/dkg255","title":"Stretching the mutant prevention concentration (MPC) beyond its limits","year":2003,"lang":"en","type":"review","venue":"Journal of Antimicrobial Chemotherapy","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Mutant; Chemistry; Microbiology; Medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000673412,0.0003952652,0.0008416621,0.00006348411,0.0001063942,0.00009644715,0.0004852165,0.0004456532,0.00004124748],"category_scores_gemma":[0.00004754085,0.0002668591,0.0009279638,0.0001472243,0.00004811911,0.00001435972,0.00002880037,0.000438897,0.00000819981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006703819,"about_ca_system_score_gemma":0.0005663275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.808267e-7,"about_ca_topic_score_gemma":0.000001535584,"domain_scores_codex":[0.9979348,0.0003288914,0.0009237594,0.0002891802,0.0002407297,0.0002826732],"domain_scores_gemma":[0.9978557,0.00002484294,0.001498437,0.0003322343,0.0002097025,0.00007909789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001110179,0.0002994643,0.000001386613,0.001605888,0.001202433,0.0000288264,0.0001157573,0.00001673991,0.3776427,0.0001101679,0.01180548,0.6070601],"study_design_scores_gemma":[0.0006067172,0.0003139896,1.834488e-7,0.001704714,0.0003067474,0.0007888257,0.00001181685,0.000002829519,0.158985,0.00003234673,0.836982,0.0002648738],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007618523,0.9896906,0.0004662289,0.0001580238,0.001066053,0.0006755361,0.000023731,0.000007899708,0.0002933791],"genre_scores_gemma":[0.0007079769,0.9966207,0.0006885235,0.0005283044,0.0008012858,0.000003897276,0.00005515755,0.00008294908,0.0005112478],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8251765,"threshold_uncertainty_score":0.9999784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02273886970744222,"score_gpt":0.3049952041377555,"score_spread":0.2822563344303133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}