{"id":"W2132502350","doi":"10.1152/ajpcell.00095.2005","title":"PAK1 induces podosome formation in A7r5 vascular smooth muscle cells in a PAK-interacting exchange factor-dependent manner","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada; Eli Lilly and Company","keywords":"Podosome; Vascular smooth muscle; PAK1; Cell biology; Smooth muscle; Actin; Chemistry; Medicine; Biology; Signal transduction; Internal medicine; Cell; Cytoskeleton; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002718155,0.000321948,0.0006608926,0.0002877461,0.00005332601,0.00001567535,0.0004335502,0.0001854387,0.00008743468],"category_scores_gemma":[0.00004745304,0.0002865149,0.0002462318,0.0002594474,0.0002100385,0.0000564723,0.0001685637,0.0004953134,0.0000238692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007801913,"about_ca_system_score_gemma":0.00008517956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000121035,"about_ca_topic_score_gemma":0.0001335944,"domain_scores_codex":[0.9977273,0.0003422985,0.0007773215,0.0004380141,0.0001669535,0.0005481538],"domain_scores_gemma":[0.9984896,0.00007364558,0.0008575652,0.0003218866,0.0001425317,0.0001147243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002488972,0.00035725,0.00007346881,0.00005500629,0.00003736094,0.000009515208,0.0006500499,0.002452735,0.9881048,0.000001940767,0.0001217731,0.007887238],"study_design_scores_gemma":[0.002433832,0.001736031,0.02793021,0.00008328419,0.0000309792,0.000031721,0.002381647,0.0002358399,0.955229,0.0001574002,0.009191487,0.0005585261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982218,0.001005193,0.0000900912,0.000136712,0.0002476769,0.0001500531,0.00001192203,0.000007468033,0.000129081],"genre_scores_gemma":[0.9970785,0.001304573,0.0003025921,0.0005065728,0.0006676008,0.00001450734,0.00004553506,0.00003702164,0.00004303618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03287572,"threshold_uncertainty_score":0.9999587,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008091309267483996,"score_gpt":0.2355181448526891,"score_spread":0.2274268355852051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}