{"id":"W2132641156","doi":"10.1152/ajprenal.00356.2007","title":"Creatine synthesis: production of guanidinoacetate by the rat and human kidney in vivo","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Renal Physiology","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Memorial University of Newfoundland; Office of Research and Development","keywords":"Creatine; Kidney; Arginine; Ornithine; Internal medicine; Endocrinology; Citrulline; In vivo; Metabolite; Creatinine; Chemistry; Glycine; Biology; Biochemistry; Amino acid; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006116152,0.0001709147,0.0004777061,0.0001049156,0.00006887926,0.000003602586,0.0002223108,0.00007670263,0.00001909683],"category_scores_gemma":[0.0002144012,0.0001168552,0.000111874,0.0001789067,0.0008455608,0.00001104602,0.00006476617,0.0001918228,4.99174e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009321739,"about_ca_system_score_gemma":0.00004242615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007678706,"about_ca_topic_score_gemma":0.00001520504,"domain_scores_codex":[0.9985341,0.0003218226,0.0005226289,0.0002601618,0.00009648842,0.0002648091],"domain_scores_gemma":[0.9987848,0.00007471369,0.0006753427,0.0002340682,0.0001413259,0.00008970274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008751141,0.000149706,0.0003858339,0.0000199478,0.0000783461,7.383859e-7,0.00005441139,0.00002226824,0.9924335,0.00006281862,0.003307974,0.002609338],"study_design_scores_gemma":[0.0005933722,0.001217841,0.05654091,0.00004435879,0.00004796369,0.00005286494,0.0002595145,0.000002060774,0.9367281,0.00055376,0.003827146,0.0001321775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986917,0.0006055076,0.00003634196,0.0003152337,0.0001810235,0.0001019677,0.0000119807,0.000002547612,0.00005366424],"genre_scores_gemma":[0.9983314,0.0005702612,0.0002126677,0.0003030981,0.0005134054,0.000006202672,0.00001555787,0.00001441476,0.00003304308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05615507,"threshold_uncertainty_score":0.4765218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005347500725722225,"score_gpt":0.2399591175875483,"score_spread":0.2346116168618261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}