{"id":"W2132698464","doi":"10.1124/mol.112.082362","title":"Induction of Multidrug Resistance Transporter ABCG2 by Prolactin in Human Breast Cancer Cells","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Abcg2; Multiple drug resistance; Prolactin; Transporter; Breast cancer; Biology; Pharmacology; Cancer research; Medicine; Cancer; Internal medicine; Drug resistance; ATP-binding cassette transporter; Gene; Hormone; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002200304,0.0001797528,0.0003642873,0.00013432,0.00003489775,0.000001937786,0.0000874672,0.0001533024,0.0005499476],"category_scores_gemma":[8.123112e-7,0.0001672921,0.0000996163,0.0002195283,0.00009361383,0.00009192205,0.000006379491,0.000301038,0.000004877331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009053314,"about_ca_system_score_gemma":0.00005084426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008169319,"about_ca_topic_score_gemma":0.00006019643,"domain_scores_codex":[0.9986842,0.00006806257,0.0003733388,0.0002477062,0.0002028677,0.0004237875],"domain_scores_gemma":[0.9995198,0.000007684847,0.0001232225,0.0001423302,0.00005925888,0.0001477578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007418166,0.0006625208,0.007983355,0.0002187879,0.00007951324,0.00006852503,0.000515278,0.00001089558,0.9879086,0.00004387269,0.001419591,0.000347256],"study_design_scores_gemma":[0.002899314,0.0000340914,0.02844005,0.00006506857,0.0002041151,0.0000113886,0.00006085453,0.000008412965,0.9640245,0.00001440269,0.004081311,0.0001565019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956318,0.001206865,0.0004642457,0.0009152403,0.0005403485,0.0005601494,0.00006301452,0.00003203954,0.0005862628],"genre_scores_gemma":[0.9979306,0.00009152573,0.000275594,0.0004827209,0.000118768,0.0001020238,0.00004412026,0.00003694969,0.0009176851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0238841,"threshold_uncertainty_score":0.6821975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007898098251346995,"score_gpt":0.2917425958676004,"score_spread":0.2838444976162534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}