{"id":"W2132726876","doi":"10.1136/gut.2010.208348","title":"Mannan-binding lectin deficiency results in unusual antibody production and excessive experimental colitis in response to mannose-expressing mild gut pathogens","year":2010,"lang":"en","type":"article","venue":"Gut","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Candida albicans; Mannan-binding lectin; Corpus albicans; Mannan; Colitis; Immunology; Biology; Microbiology; Antibody; Lectin; Inflammatory bowel disease; Disease; Medicine; Polysaccharide; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001777587,0.0007172108,0.0004327624,0.0006648876,0.0002159132,0.0003697722,0.00023882,0.0006569878,0.001832155],"category_scores_gemma":[0.0003004275,0.0003251974,0.0003470131,0.0002799493,0.0005273949,0.0001943058,0.0003532324,0.0007827474,0.0003465607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002810656,"about_ca_system_score_gemma":0.0001648217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002456122,"about_ca_topic_score_gemma":0.0003910045,"domain_scores_codex":[0.9996612,0.00005353607,0.00005871035,0.00009724705,0.00006021576,0.0000690331],"domain_scores_gemma":[0.9992707,0.00009215392,0.000236458,0.00005827037,0.0000234737,0.0003188673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007689518,0.0001295056,0.002183874,0.00005910761,0.00001764374,0.0006587824,0.00001995351,0.00004032804,0.9952885,0.00004132965,0.0000434655,0.0007484897],"study_design_scores_gemma":[0.0002949255,0.003753856,0.1815567,0.00007120906,0.0001507853,0.02880579,0.0001810267,0.001363688,0.7807195,0.0001944782,0.002871272,0.00003672912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984118,0.0004589403,0.0005051445,0.00003228614,0.00000925151,0.00001498521,0.0002386364,0.00004414209,0.0002847983],"genre_scores_gemma":[0.9976785,0.0002502231,0.0009424906,0.00004739923,0.000008363677,0.00002413861,0.0004384954,0.00002532524,0.0005852074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001832155,"threshold_uncertainty_score":0.006129205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02122207100785602,"score_gpt":0.3192109125848738,"score_spread":0.2979888415770178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}