{"id":"W2132747619","doi":"10.1530/eje.0.1470591","title":"Serum GH response to pharmacological stimuli and physical exercise in two siblings with two new inactivating mutations in the GH-releasing hormone receptor gene","year":2002,"lang":"en","type":"article","venue":"European Journal of Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Institute of Nutrition, Metabolism and Diabetes","funders":"National Center for Research Resources; Genentech; National Institutes of Health","keywords":"IGHD; Endocrinology; Internal medicine; Intron; Biology; Exon; Genetics; Mutation; Gene; Growth hormone deficiency; Hormone; Growth hormone; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004658784,0.0002201776,0.0004716183,0.0005565615,0.00008854933,0.00003261099,0.0002127201,0.00001961982,0.00003905478],"category_scores_gemma":[0.0005051325,0.0001450262,0.00006609367,0.0007004454,0.0001267677,0.0001958879,0.00007505505,0.0009685386,0.00003180441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008473826,"about_ca_system_score_gemma":0.00006015513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002578334,"about_ca_topic_score_gemma":0.000002293416,"domain_scores_codex":[0.9975748,0.0008486309,0.0005880792,0.0002538193,0.0002628577,0.0004718358],"domain_scores_gemma":[0.9987825,0.0004750347,0.0002384781,0.0001475931,0.0001074599,0.0002489474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01835627,0.001552612,0.03088176,0.00002682819,0.0001747151,0.01396233,0.02614918,0.0009937417,0.7920615,0.00007967948,0.003349758,0.1124116],"study_design_scores_gemma":[0.03278438,0.01003283,0.921644,0.0005214562,0.0003445844,0.005154234,0.00506901,0.0009065123,0.01892316,0.0000904765,0.003957761,0.0005715597],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914612,0.0007178633,0.0001454422,0.006650347,0.00007649011,0.0002961862,0.000002130824,0.00001832762,0.0006320557],"genre_scores_gemma":[0.9954124,0.0003312993,0.00296697,0.0008644992,0.000314125,0.000003121143,0.000001288207,0.00003363886,0.00007262411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8907623,"threshold_uncertainty_score":0.5913997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0434190310994576,"score_gpt":0.3127627714208869,"score_spread":0.2693437403214293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}