{"id":"W2132779385","doi":"10.1128/mcb.00214-12","title":"Protein Tyrosine Phosphatase <i>α</i> Phosphotyrosyl-789 Binds BCAR3 To Position Cas for Activation at Integrin-Mediated Focal Adhesions","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Focal adhesion; Integrin; Biology; Proto-oncogene tyrosine-protein kinase Src; Protein tyrosine phosphatase; Cell biology; Phosphorylation; Tyrosine phosphorylation; Scaffold protein; Phosphatase; Actin cytoskeleton; PTK2; Extracellular matrix; Signal transduction; Cell adhesion; Cytoskeleton; Receptor; Biochemistry; Cell; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009754726,0.0003640611,0.0001894555,0.0001588637,0.000288653,0.0003708168,0.0002715986,0.0002757945,0.00282471],"category_scores_gemma":[0.0001150684,0.0001212582,0.0003001072,0.0001772993,0.0002391924,0.0002603338,0.0002919896,0.0005749418,0.001512856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006410824,"about_ca_system_score_gemma":0.0002141226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001044374,"about_ca_topic_score_gemma":0.001015546,"domain_scores_codex":[0.9998688,0.00001413914,0.000005483655,0.00003366284,0.00003596415,0.00004195918],"domain_scores_gemma":[0.9999372,0.000005319158,0.00001986863,0.000006818311,0.000007629435,0.00002314476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000312414,0.000008181587,0.000251462,0.00000692364,0.000002254645,0.0000872072,0.000005658972,0.00003678228,0.998652,0.0002073039,0.00004393169,0.0006670383],"study_design_scores_gemma":[0.00001105371,0.00005810718,0.007062717,0.000002202544,0.000005028611,0.0007683242,0.00001907358,0.001177142,0.9877224,0.0001396761,0.003031048,0.000003222832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840015,0.001140499,0.009046624,0.00021264,0.00004127914,0.00002522884,0.0002441054,0.0001734584,0.005114703],"genre_scores_gemma":[0.9935694,0.0003590631,0.003121895,0.000055758,0.00001275098,0.0000100508,0.0003147797,0.00001966268,0.00253658],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00282471,"threshold_uncertainty_score":0.009449661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008689614500418625,"score_gpt":0.2459688490784313,"score_spread":0.2372792345780126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}