{"id":"W2132913823","doi":"10.1128/iai.00735-07","title":"Comparisons of Mutants Lacking the Golgi UDP-Galactose or GDP-Mannose Transporters Establish that Phosphoglycans Are Important for Promastigote but Not Amastigote Virulence in <i>Leishmania major</i>","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; McMaster University","keywords":"Lipophosphoglycan; Biology; Amastigote; Virulence; Glycoconjugate; Mutant; Leishmania; Mannose; Microbiology; Leishmania major; Leishmania mexicana; Macrophage; Leishmania donovani; Phenotype; Cell biology; Biochemistry; Gene; Parasite hosting; Immunology; In vitro; Leishmaniasis; Visceral leishmaniasis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001051051,0.0006169551,0.0002579429,0.0003348537,0.0001132968,0.0002647126,0.0003650466,0.0004531628,0.0009689378],"category_scores_gemma":[0.0001527142,0.00017431,0.000452973,0.0002207313,0.0002683759,0.0002324706,0.000368804,0.0005061448,0.0002934985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003308279,"about_ca_system_score_gemma":0.00013346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009671187,"about_ca_topic_score_gemma":0.00082542,"domain_scores_codex":[0.9998455,0.00002053459,0.00003094551,0.00003410885,0.00003198777,0.00003687213],"domain_scores_gemma":[0.9997362,0.00004259195,0.00009412848,0.00002764629,0.00002152783,0.00007775133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001961552,0.0000373738,0.0003129882,0.00002037946,0.00001008365,0.00006731719,0.00001547609,0.00005157855,0.998812,0.00006669485,0.00000839154,0.0004015978],"study_design_scores_gemma":[0.0000303237,0.001018829,0.01394726,0.000009628396,0.00006544294,0.0009558681,0.0001031823,0.001189674,0.9813607,0.00006154653,0.001244116,0.00001360078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978879,0.0001952227,0.0008970786,0.00001528172,0.000009364222,0.00002356906,0.0004703907,0.0000278985,0.000473354],"genre_scores_gemma":[0.9945629,0.0002453144,0.001995401,0.00003782279,0.000004725507,0.00005402488,0.001630395,0.00005297206,0.001416285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009689378,"threshold_uncertainty_score":0.00324142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05440739424256743,"score_gpt":0.3222764564795794,"score_spread":0.267869062237012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}