{"id":"W2132940815","doi":"10.1093/annonc/mdl355","title":"Dose-dense adjuvant chemotherapy in node-positive breast cancer: docetaxel followed by epirubicin/cyclophosphamide (T/EC), or the reverse sequence (EC/T), every 2 weeks, versus docetaxel, epirubicin and cyclophosphamide (TEC) every 3 weeks. AERO B03 randomized phase II study","year":2006,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Collège Montmorency","funders":"Sanofi; Amgen","keywords":"Medicine; Epirubicin; Docetaxel; Regimen; Internal medicine; Cyclophosphamide; Gastroenterology; Febrile neutropenia; Anthracycline; Breast cancer; Neutropenia; Chemotherapy regimen; Taxane; Chemotherapy; Oncology; Surgery; Urology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001312076,0.0008790562,0.002114613,0.0001569822,0.0003912658,0.00003349849,0.0005588402,0.0004486336,0.0001264048],"category_scores_gemma":[0.0002566648,0.0006010818,0.0004184974,0.0005153209,0.001200746,0.00005376462,0.0003848571,0.000405793,0.000009449824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000232898,"about_ca_system_score_gemma":0.0006198207,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01367287,"about_ca_topic_score_gemma":0.004216051,"domain_scores_codex":[0.9949841,0.0008981924,0.001339345,0.001296031,0.0004588736,0.001023476],"domain_scores_gemma":[0.9968863,0.0007887058,0.0009134055,0.0008004535,0.0004210667,0.0001901031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7057801,0.01212802,0.01672184,0.0001286977,0.005001704,0.0007039181,0.002426852,0.0002893442,0.1032546,0.00005747761,0.10152,0.05198742],"study_design_scores_gemma":[0.7355835,0.01565035,0.06512957,0.000403073,0.001679937,0.0003507755,0.002697435,0.00007746578,0.1288302,0.0002963801,0.0469979,0.00230344],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9648844,0.01940281,0.00002239598,0.01088147,0.0006475359,0.002377979,0.001077833,0.00004509956,0.0006604953],"genre_scores_gemma":[0.9746762,0.01983903,0.0001789347,0.002800733,0.0002972555,0.0007403612,0.0001781394,0.00009362814,0.001195752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05452213,"threshold_uncertainty_score":0.999644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02555265505985911,"score_gpt":0.3412828668037834,"score_spread":0.3157302117439243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}