{"id":"W2132994701","doi":"10.1021/jo070664s","title":"Intramolecular Conjugate Displacement:  A General Route to Hexahydroquinolizines, Hexahydroindolizines, and Related [<i>m</i>,<i>n</i>,0]-Bicyclic Structures with Nitrogen at a Bridgehead","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Bicyclic molecule; Chemistry; Carbanion; Allylic rearrangement; Aldehyde; Intramolecular force; Intramolecular reaction; Stereochemistry; Conjugate; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001463038,0.0005355827,0.000197279,0.0002027894,0.0001965479,0.0002176202,0.0005518839,0.0002757519,0.00391358],"category_scores_gemma":[0.0001113808,0.0001947123,0.0001975881,0.0001861489,0.0003122411,0.0003587323,0.0005160061,0.0005401879,0.001531449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000335848,"about_ca_system_score_gemma":0.0004556852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004767835,"about_ca_topic_score_gemma":0.0009206921,"domain_scores_codex":[0.9998955,0.000009801193,0.000008308461,0.00003528159,0.00002192715,0.00002912662],"domain_scores_gemma":[0.9999621,0.000004393979,0.000008440586,0.000009184023,0.000007297937,0.00000860031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002264266,0.000149933,0.0003776327,0.0004290708,0.00003602054,0.0007842886,0.0003022811,0.001191461,0.9207157,0.03038247,0.001801096,0.04360368],"study_design_scores_gemma":[0.00007233817,0.0007256294,0.0006162411,0.00001312533,0.00002085001,0.00101247,0.00002593836,0.0006584986,0.9581443,0.001131656,0.0375528,0.00002612592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7156195,0.005998711,0.1530292,0.00106168,0.0007101151,0.001301736,0.001702311,0.00140552,0.1191712],"genre_scores_gemma":[0.9512115,0.002307634,0.02386352,0.0001908058,0.00004124454,0.0002162775,0.0004626799,0.00006360219,0.02164272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00391358,"threshold_uncertainty_score":0.01309222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003802989849551942,"score_gpt":0.2025285376369645,"score_spread":0.1987255477874126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}