{"id":"W2133033875","doi":"10.1093/hmg/ddh197","title":"Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase","year":2004,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":241,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Cytochrome c oxidase; Biology; Phenotype; Mutant; Fusion protein; Electron Transport Complex IV; Transfection; Cell biology; Gene; Mitochondrion; Recombinant DNA; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001738404,0.0006410616,0.0002354557,0.000401296,0.0002356936,0.0003490284,0.000233318,0.0003876472,0.0009909052],"category_scores_gemma":[0.0003914215,0.0001761049,0.0003009909,0.0003757994,0.0003057626,0.0001977431,0.0002901445,0.000230576,0.0005441907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306788,"about_ca_system_score_gemma":0.0002827427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006851733,"about_ca_topic_score_gemma":0.0008718058,"domain_scores_codex":[0.9998263,0.00002054663,0.00001801336,0.00005248653,0.00005230175,0.00003037279],"domain_scores_gemma":[0.9996544,0.00004935549,0.0001150615,0.00004614662,0.00003174361,0.0001033076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003342762,0.00004312076,0.007592776,0.0000680344,0.00002511875,0.0009969067,0.000109436,0.0001407231,0.9880029,0.0003598014,0.0001402081,0.002186681],"study_design_scores_gemma":[0.0001405093,0.000481923,0.1018165,0.00002432635,0.00008648424,0.01653468,0.0001661357,0.003769231,0.8656117,0.0004268469,0.01090551,0.00003613023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971559,0.000519219,0.001429291,0.00006016535,0.00001146633,0.00001406782,0.0002346555,0.00003772891,0.000537509],"genre_scores_gemma":[0.9957334,0.0002624927,0.001493755,0.00003963753,0.00001059773,0.00001634902,0.0009941359,0.00001801247,0.001431679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009909052,"threshold_uncertainty_score":0.003314853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01578271029682269,"score_gpt":0.272532090471245,"score_spread":0.2567493801744223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}