{"id":"W2133049833","doi":"10.1016/j.jaci.2009.11.042","title":"A novel allergen-specific therapy for allergy using CD40-silenced dendritic cells","year":2010,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Allergy; Allergen; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004598312,0.0001884087,0.0003766625,0.00006884226,0.0001033118,0.00002892708,0.000365552,0.0004997228,0.00009176219],"category_scores_gemma":[0.0001071821,0.0001570382,0.0003510557,0.00004314085,0.0002952772,0.00001326824,0.00008959934,0.0004378467,0.000003805935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005423967,"about_ca_system_score_gemma":0.0001266913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008477802,"about_ca_topic_score_gemma":0.00008008295,"domain_scores_codex":[0.9984103,0.0000726971,0.000838746,0.0002935444,0.00009173014,0.0002929124],"domain_scores_gemma":[0.9987297,0.0001192035,0.0004000595,0.0002713657,0.0003663867,0.0001132661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001337425,0.0003360687,0.0001106394,0.000001674636,0.001202498,0.00000723747,0.00002947685,0.00002166734,0.9860426,0.0001739115,0.001192074,0.009544704],"study_design_scores_gemma":[0.01021274,0.009835723,0.0145307,0.0000652667,0.00005015964,0.0009461934,0.0004945201,0.0002656528,0.3655696,0.0007460944,0.5965459,0.0007374106],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866354,0.004756392,0.005769638,0.0002291075,0.002441367,0.0001005372,0.000007279174,0.00000376762,0.00005650345],"genre_scores_gemma":[0.9332882,0.05715923,0.007364098,0.0006287913,0.001264104,0.000005460096,0.00001274327,0.00003181385,0.0002455762],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.620473,"threshold_uncertainty_score":0.640383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03803410746117758,"score_gpt":0.3219831888582158,"score_spread":0.2839490813970382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}