{"id":"W2133093811","doi":"10.2353/jmoldx.2008.070082","title":"Molecular Classification and Correlates in Colorectal Cancer","year":2007,"lang":"en","type":"review","venue":"Journal of Molecular Diagnostics","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":461,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; Gary Bennett Family Fund; National Cancer Institute; Entertainment Industry Foundation","keywords":"Microsatellite instability; Colorectal cancer; Cancer; Biology; Chromosome instability; Carcinogenesis; Epigenomics; DNA methylation; Molecular marker; Bioinformatics; Oncology; Medicine; Genetics; Microsatellite; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001033683,0.0007698184,0.001788053,0.003256084,0.0001965011,0.001101228,0.001087974,0.000834914,0.001351264],"category_scores_gemma":[0.002093224,0.000332925,0.0005123275,0.004031059,0.0006719864,0.001245881,0.0005367182,0.001376046,0.0009243067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008154662,"about_ca_system_score_gemma":0.001301353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001788818,"about_ca_topic_score_gemma":0.002494806,"domain_scores_codex":[0.9996595,0.00007058115,0.00006588003,0.00006354645,0.0001139653,0.00002657132],"domain_scores_gemma":[0.9989823,0.0005104961,0.0002166168,0.0000232853,0.0002200593,0.00004730721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009603043,0.00004760738,0.002212402,0.00840699,0.0001268685,0.0002424486,0.00003477488,0.0003271806,0.0007167471,0.00203333,0.02593648,0.9598193],"study_design_scores_gemma":[0.00005382417,0.0001831847,0.01201347,0.00942249,0.0007416605,0.004561151,0.0001530218,0.0004180016,0.0008634228,0.00371894,0.9678103,0.00006056308],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000171878,0.9987902,0.0001435609,0.0003271048,0.0002158335,0.000003061285,0.00001636986,0.000004481054,0.0003274684],"genre_scores_gemma":[0.001104922,0.9976875,0.00030665,0.000219267,0.0003912426,0.000004335364,0.00004191502,0.000001030716,0.0002433069],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003256084,"threshold_uncertainty_score":0.005916655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04701968899797475,"score_gpt":0.3731771762075239,"score_spread":0.3261574872095492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}