{"id":"W2133115356","doi":"10.1186/ar4449","title":"High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain","year":2014,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Rheumatology; Intervertebral disc; Degeneration (medical); Medicine; Strain (injury); Secretion; Inflammation; Internal medicine; Pathology; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001862662,0.0001463392,0.0004436036,0.0001717944,0.00005328412,0.00001741977,0.00009898076,0.0001363975,0.0001996552],"category_scores_gemma":[0.0003796156,0.0001038059,0.00008245562,0.0001762483,0.000350197,0.0001639143,0.00004993136,0.0002812487,0.000001568814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000444217,"about_ca_system_score_gemma":0.0000665269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000823677,"about_ca_topic_score_gemma":0.0002411272,"domain_scores_codex":[0.9975455,0.001021493,0.0003910824,0.0002690904,0.0004784795,0.0002943128],"domain_scores_gemma":[0.9991506,0.000110579,0.0001214731,0.0002290938,0.0002715827,0.0001166745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000161373,0.0003261121,0.009139867,0.00007580191,0.00008881676,0.000008009849,0.0007222631,0.000001098169,0.9043168,0.001648668,0.0001809183,0.0833303],"study_design_scores_gemma":[0.005366877,0.01468496,0.4011233,0.001184258,0.00001469137,0.000007854906,0.0004681844,0.001181724,0.5741387,0.001563529,0.00005974621,0.0002062144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970804,0.000336188,0.001491933,0.000368527,0.00003300828,0.0005379825,0.00004679153,0.00002434816,0.00008077501],"genre_scores_gemma":[0.9987169,0.0004488146,0.0003485889,0.00007134389,0.00004731278,0.00003151117,0.0002476938,0.00002544189,0.00006240739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3919834,"threshold_uncertainty_score":0.4233082,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04354340759063459,"score_gpt":0.2991067174796311,"score_spread":0.2555633098889965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}