{"id":"W2133127556","doi":"10.1128/mcb.26.4.1496-1509.2006","title":"Evidence that Spt2/Sin1, an HMG-Like Factor, Plays Roles in Transcription Elongation, Chromatin Structure, and Genome Stability in <i>Saccharomyces cerevisiae</i>","year":2006,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université Laval; Hôtel-Dieu de Québec","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Chromatin; Transcription coregulator; Chromatin immunoprecipitation; Genetics; Saccharomyces cerevisiae; Transcription (linguistics); Transcription factor; Promoter; Histone; Gene; Cell biology; Chromatin remodeling; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001978402,0.0003583108,0.0001066306,0.0003289017,0.0002211742,0.0003700356,0.0001753833,0.0003077193,0.001841074],"category_scores_gemma":[0.0002161293,0.0001197037,0.0002270756,0.0002452394,0.0003160441,0.000195712,0.0002315113,0.0003310832,0.0004857868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003356053,"about_ca_system_score_gemma":0.000303152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001255577,"about_ca_topic_score_gemma":0.002018709,"domain_scores_codex":[0.9999036,0.0000132207,0.000007290095,0.00002441472,0.00003619998,0.00001523208],"domain_scores_gemma":[0.9997507,0.00006106644,0.00004268764,0.00003106329,0.00004578038,0.00006881539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003092132,0.00001914827,0.005807965,0.0001714581,0.00003292007,0.0003636895,0.00002777758,0.0001548475,0.9878468,0.0003415452,0.0002503076,0.004674252],"study_design_scores_gemma":[0.00006388689,0.0002656764,0.1124013,0.00004758004,0.0001073882,0.002962531,0.0001478284,0.002602705,0.8669407,0.0008388172,0.01360252,0.00001914803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778873,0.01181102,0.004087849,0.0005897746,0.00006474458,0.000008579942,0.0008397878,0.0001276491,0.004583331],"genre_scores_gemma":[0.9902251,0.003309389,0.002146556,0.0001862897,0.00003371031,0.000007266973,0.002191793,0.00002303507,0.001876785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001841074,"threshold_uncertainty_score":0.006159008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01118349732531824,"score_gpt":0.2137196139938865,"score_spread":0.2025361166685683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}