{"id":"W2133152337","doi":"10.1016/j.jcjd.2013.08.174","title":"Lkb1 Depletion Enhances Insulin Secretion and K+ATP Channel Closure Despite Impairing Glucose Metabolism","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Ontario","funders":"","keywords":"Diazoxide; Internal medicine; Insulin; Endocrinology; Carbohydrate metabolism; Secretion; Biology; Metabolism; Beta cell; Protein kinase A; Kinase; Cell biology; Islet; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003120783,0.000550877,0.0009420625,0.000373623,0.0005346888,0.001064929,0.000665585,0.0007996911,0.005108926],"category_scores_gemma":[0.0004616562,0.0004772045,0.000536709,0.0003204843,0.0009811789,0.0006476038,0.0006563763,0.002277633,0.00138376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007060206,"about_ca_system_score_gemma":0.0008454057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001995535,"about_ca_topic_score_gemma":0.002903905,"domain_scores_codex":[0.9995103,0.0000538876,0.00006885923,0.00008589585,0.00009077551,0.0001902857],"domain_scores_gemma":[0.9994019,0.0001020265,0.0001304499,0.00006970524,0.00004900519,0.0002468625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004475623,0.0002534466,0.0004442437,0.0001606796,0.00004072294,0.0002544832,0.00005499849,0.0001454009,0.9910745,0.0003294215,0.0007094009,0.002057081],"study_design_scores_gemma":[0.0004381061,0.001305445,0.009285859,0.00003463747,0.0001122425,0.0007465308,0.0003172812,0.001273308,0.9798507,0.0002368728,0.006364794,0.00003414805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922395,0.001960782,0.0009540111,0.0008089552,0.0003192211,0.0000339688,0.0009483977,0.0003509985,0.002384095],"genre_scores_gemma":[0.9945887,0.0007144414,0.000816933,0.0002332461,0.00003963987,0.00006267781,0.0007944076,0.00009482143,0.002655198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005108926,"threshold_uncertainty_score":0.01709104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009463962915160532,"score_gpt":0.2096815113350314,"score_spread":0.2002175484198708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}