{"id":"W2133193857","doi":"10.1111/j.1365-294x.2009.04313.x","title":"Genomic reaction norms: using integrative biology to understand molecular mechanisms of phenotypic plasticity","year":2009,"lang":"en","type":"review","venue":"Molecular Ecology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":352,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences","keywords":"Biology; Phenotypic plasticity; Epigenetics; Organism; DNA methylation; Evolutionary biology; Computational biology; Phenotype; DNA microarray; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002221837,0.0006964479,0.001661282,0.0003341573,0.00008410274,0.00002004382,0.0005860533,0.001140773,0.00001709057],"category_scores_gemma":[0.0001481359,0.0006596866,0.0005781979,0.0002712733,0.0001382309,0.000003085843,0.000354544,0.0003537444,0.00001987162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003337016,"about_ca_system_score_gemma":0.0005904574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003094396,"about_ca_topic_score_gemma":0.0001035156,"domain_scores_codex":[0.9971004,0.0003600492,0.0008809345,0.0009603311,0.0001184467,0.0005798315],"domain_scores_gemma":[0.9983217,0.00004050269,0.0006776781,0.0006283425,0.0001610201,0.0001707578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007421576,0.0002770128,0.000004374798,0.001369841,0.001090876,0.00006205439,0.000070323,0.0008569575,0.9279292,0.01252173,0.00005171586,0.0556917],"study_design_scores_gemma":[0.007252088,0.02490896,0.0002440277,0.00824684,0.01485808,0.002367588,0.001453129,0.003071804,0.2031396,0.105388,0.614843,0.01422691],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07373912,0.5763883,0.346792,0.00002810685,0.0005383702,0.001773728,0.0002585702,0.00002766775,0.0004541418],"genre_scores_gemma":[0.07260719,0.8988553,0.02563569,0.0006442523,0.0001833092,0.00009664619,0.001579719,0.0003016569,0.00009622877],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7247896,"threshold_uncertainty_score":0.9995854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791798398839173,"score_gpt":0.2846557841996432,"score_spread":0.2667378002112514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}