{"id":"W2133215208","doi":"10.1091/mbc.e09-11-0947","title":"TBC-2 Regulates RAB-5/RAB-7-mediated Endosomal Trafficking in<i>Caenorhabditis elegans</i>","year":2010,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital; McGill University Health Centre; Royal Victoria Regional Health Centre","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Rutgers, The State University of New Jersey","keywords":"Rab; Endosome; Cell biology; Biology; GTPase; Caenorhabditis elegans; Small GTPase; Guanine nucleotide exchange factor; Transport protein; Lysosome; GTPase-activating protein; Biochemistry; Signal transduction; G protein; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009432346,0.0006556926,0.0002247928,0.0003175736,0.0003823391,0.0004219474,0.0003816863,0.0004057488,0.0008596321],"category_scores_gemma":[0.0001091782,0.0002761716,0.0002753187,0.00009339818,0.0003213269,0.0001524071,0.0003430994,0.0005060746,0.0005424026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001127433,"about_ca_system_score_gemma":0.0003085057,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006461974,"about_ca_topic_score_gemma":0.01253536,"domain_scores_codex":[0.9998626,0.0000106739,0.00001192139,0.00003931866,0.00004123744,0.00003426182],"domain_scores_gemma":[0.9998178,0.00001838391,0.00005835311,0.00001337648,0.00002430994,0.00006770784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004134799,0.00001295225,0.0001818819,0.00001877476,0.000002662814,0.0000737633,0.00001015024,0.00006375371,0.9992519,0.00004141892,0.00005949559,0.0002418451],"study_design_scores_gemma":[0.00003741921,0.0001096513,0.01448335,0.00001910636,0.00002440967,0.0002800199,0.0000641662,0.003695272,0.9782948,0.00004950206,0.002923683,0.00001861997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956478,0.0006477314,0.0009424261,0.00007253479,0.0000260108,0.00002613622,0.0004869645,0.0001734593,0.001976935],"genre_scores_gemma":[0.9937781,0.0003268612,0.001506557,0.00008769273,0.00000696088,0.00004731106,0.0006833592,0.00008438525,0.003478805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006461974,"threshold_uncertainty_score":0.01284873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002720942974080453,"score_gpt":0.1923184138270328,"score_spread":0.1895974708529524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}