{"id":"W2133318565","doi":"10.1186/1750-1326-7-54","title":"Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP","year":2012,"lang":"en","type":"article","venue":"Molecular Neurodegeneration","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Institute of Genetics; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Johns Hopkins University","keywords":"Stress granule; Endogeny; Neurology; Neuroscience; Chemistry; Medicine; Biology; Internal medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002895793,0.0002576228,0.0003303861,0.0001838971,0.0001829817,0.00009026369,0.0001668162,0.0001441816,0.00007632401],"category_scores_gemma":[0.0002230504,0.0002345652,0.0001256894,0.0003507598,0.00004097878,0.0001757139,0.0001190151,0.0002706689,0.0003170632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001510728,"about_ca_system_score_gemma":0.00006888973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002222318,"about_ca_topic_score_gemma":0.0000231486,"domain_scores_codex":[0.9975327,0.0002308701,0.0003568152,0.0004308839,0.0007046438,0.0007441301],"domain_scores_gemma":[0.9986148,0.00003885954,0.00006545968,0.0005580073,0.0002641495,0.0004586538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001511689,0.0002333019,0.002754456,0.00002590256,0.00004415834,0.00008680684,0.00008149652,0.0003176415,0.9910201,0.0003353061,0.0005088248,0.004440795],"study_design_scores_gemma":[0.0009892212,0.0002974006,0.04132649,0.00002481086,0.00007093934,0.00006484703,0.000005787295,0.001179786,0.9543415,0.000012994,0.001485366,0.0002008343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9574437,0.0004600736,0.03709377,0.003040036,0.0003665196,0.001007934,0.00003414706,0.0001102538,0.0004436126],"genre_scores_gemma":[0.9937868,0.00003343801,0.0008030006,0.004066259,0.0004995507,0.0001213015,0.0002045768,0.00007027089,0.0004147871],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03857203,"threshold_uncertainty_score":0.956529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03688788026256299,"score_gpt":0.2786164819175051,"score_spread":0.2417286016549421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}