{"id":"W2133372930","doi":"10.1177/1091581809337918","title":"Effects of Mixtures of Polychlorinated Biphenyls, Methylmercury, and Organochlorine Pesticides on Hepatic DNA Methylation in Prepubertal Female Sprague-Dawley Rats","year":2009,"lang":"en","type":"article","venue":"International Journal of Toxicology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"DNA methylation; Methylation; Methylmercury; Offspring; Chemistry; Epigenetics; CpG site; Andrology; Internal medicine; Molecular biology; Endocrinology; Biology; Gene expression; DNA; Gene; Pregnancy; Environmental chemistry; Biochemistry; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003654519,0.0001264944,0.0002914696,0.0002994033,0.0000126286,0.000008554341,0.0001936688,0.0001461142,0.00001092516],"category_scores_gemma":[0.0009207183,0.0001137152,0.00008066042,0.0000987584,0.0000678043,0.00001266032,0.00004088391,0.0001177929,3.315218e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002731099,"about_ca_system_score_gemma":0.00007015075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000198882,"about_ca_topic_score_gemma":0.00002481408,"domain_scores_codex":[0.9987624,0.0001480316,0.0005766897,0.0001584178,0.0002360401,0.0001184693],"domain_scores_gemma":[0.9987645,0.0002011035,0.0005405678,0.00009500438,0.0003450493,0.00005381401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006132344,0.0003063845,0.006489803,0.00002190073,0.0001076947,0.00002575702,0.0001156559,0.0004651166,0.9820439,0.000245394,0.000008833213,0.009556295],"study_design_scores_gemma":[0.000936815,0.002008831,0.1224202,0.00006020007,0.00003123798,0.00002171597,0.0000141287,0.00006784098,0.8730457,0.001226081,0.0000881664,0.00007904619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961183,0.001949623,0.0009330968,0.0002823207,0.0004533429,0.0001284027,0.000004522668,0.000001800625,0.0001286123],"genre_scores_gemma":[0.9981859,0.0006584184,0.0008780537,0.00007177521,0.0001584066,0.000002087405,0.00001163211,0.000009166053,0.0000245688],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1159304,"threshold_uncertainty_score":0.4637173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007404183271289105,"score_gpt":0.2800986946830326,"score_spread":0.2726945114117434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}