{"id":"W2133401213","doi":"10.1093/intimm/13.3.321","title":"The non-classical MHC class I molecule Qa-1b inhibits classical MHC class I-restricted cytotoxicity of cytotoxic T lymphocytes","year":2001,"lang":"en","type":"article","venue":"International Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"National Cancer Institute; BC Cancer Agency; Deutsche Forschungsgemeinschaft","keywords":"Cytotoxic T cell; MHC class I; CD8; Molecular biology; Cytotoxicity; Chemistry; Antigen-presenting cell; Biology; Antigen; Cell biology; In vitro; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002773568,0.0004320278,0.0005446463,0.0003759107,0.0004512321,0.00007002464,0.0009942416,0.0007729926,0.001478686],"category_scores_gemma":[0.000639302,0.0003464674,0.0003713201,0.0004046659,0.001080245,0.0003018781,0.0003991827,0.00105386,0.001779677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005010749,"about_ca_system_score_gemma":0.0002475152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002414839,"about_ca_topic_score_gemma":0.00006007315,"domain_scores_codex":[0.9969118,0.0004807678,0.001095867,0.000600646,0.0001959112,0.0007150373],"domain_scores_gemma":[0.9973089,0.0008489761,0.0005859255,0.0006241308,0.0005849855,0.00004710411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002170053,0.0007072178,0.0006528602,0.000005070296,0.0008960573,0.00002220095,0.0001243123,0.00004738182,0.9658328,0.006595887,0.02056797,0.002378211],"study_design_scores_gemma":[0.004279617,0.0007009727,0.009782858,0.00006165234,0.000061639,0.0007630558,0.0003475918,0.001299381,0.601186,0.0002529945,0.3808676,0.0003966857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9591188,0.001383087,0.001161158,0.005361517,0.01069084,0.000474444,0.00003090279,0.0001852267,0.02159404],"genre_scores_gemma":[0.9677776,0.0008505406,0.00002653016,0.0005401319,0.0001811237,0.0001054502,0.0002926654,0.00004492817,0.0301811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3646468,"threshold_uncertainty_score":0.9998987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070335620126068,"score_gpt":0.2456886649371205,"score_spread":0.2349853087358598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}