{"id":"W2133407991","doi":"10.1371/journal.pone.0020034","title":"Genistein Increases Epidermal Growth Factor Receptor Signaling and Promotes Tumor Progression in Advanced Human Prostate Cancer","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Phytoestrogen effects and research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Genistein; Prostate cancer; Cancer research; Cancer; In vivo; Medicine; Metastasis; Prostate; Apoptosis; Cell growth; Epidermal growth factor receptor; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008271229,0.0002919412,0.0002750926,0.0003959091,0.0001399198,0.0001742766,0.00006541072,0.0001592344,0.00147503],"category_scores_gemma":[0.00006018013,0.00009466687,0.0002153724,0.0002382533,0.0001160243,0.00009254945,0.0001253564,0.0003736925,0.0002548997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001771589,"about_ca_system_score_gemma":0.0002440349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001718682,"about_ca_topic_score_gemma":0.004299014,"domain_scores_codex":[0.999945,0.0000120751,0.000002795669,0.000008772713,0.00001456189,0.0000168155],"domain_scores_gemma":[0.9999603,0.000006756302,0.000006066265,0.000003769537,0.000004831962,0.00001818728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007989035,0.0001684996,0.0009288097,0.00006518647,0.00001424525,0.00009396086,0.00003051074,0.0000766096,0.9939297,0.00003870286,0.0001098842,0.003744901],"study_design_scores_gemma":[0.0001138517,0.004781609,0.09721224,0.00001883466,0.00009733871,0.000671819,0.0001229902,0.0007042345,0.8872788,0.0001436626,0.008842714,0.00001197893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912964,0.005719073,0.0006209194,0.0001099379,0.00002371567,0.00002874171,0.0004069612,0.0001018424,0.001692326],"genre_scores_gemma":[0.9935789,0.002823174,0.0004789209,0.00004706807,0.00001067078,0.00001912726,0.0004046734,0.000008937127,0.002628547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001718682,"threshold_uncertainty_score":0.00493449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06597077980531771,"score_gpt":0.3164112363023975,"score_spread":0.2504404564970798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}