{"id":"W2133491083","doi":"10.1101/gad.208701","title":"The yeast Xrs2 complex functions in S phase checkpoint regulation","year":2001,"lang":"en","type":"article","venue":"Genes & Development","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; G2-M DNA damage checkpoint; DNA damage; Rad50; Saccharomyces cerevisiae; CHEK1; Nijmegen breakage syndrome; DNA repair; Cell biology; Cell cycle checkpoint; Checkpoint Kinase 2; Nuclease; Mutation; Cell cycle; Genetics; DNA; DNA-binding protein; Yeast; Gene; Transcription factor; Ataxia-telangiectasia","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002300041,0.000105198,0.0000715581,0.00003136643,0.0001589985,0.00002279657,0.0001207191,0.00005950804,0.00005963751],"category_scores_gemma":[0.00001645236,0.00008608988,0.00003510939,0.0001016688,0.00002703539,0.000002417904,0.0000886039,0.00003680903,0.00006373048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004447511,"about_ca_system_score_gemma":0.0001017595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007152987,"about_ca_topic_score_gemma":0.0002977849,"domain_scores_codex":[0.9991797,0.00003336057,0.0002289473,0.0002247923,0.0001202362,0.0002129769],"domain_scores_gemma":[0.9996071,0.000003996262,0.00005130059,0.0002442506,0.0000466028,0.00004674866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007306826,0.00008390533,0.0009027096,0.000002627334,0.0000252965,0.000003001302,0.00007933619,0.00008250331,0.8520375,0.00007788038,0.001209604,0.1454226],"study_design_scores_gemma":[0.000664551,0.00005438815,0.01937121,0.000005620208,0.00000407927,0.00002255121,0.0001219955,0.0002070599,0.3187676,0.0001502577,0.6604876,0.0001430898],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907277,0.0003788699,0.006596958,0.000246626,0.000234746,0.000210259,0.000002571277,0.00001987355,0.001582403],"genre_scores_gemma":[0.9927979,0.0001265745,0.003501577,0.0001115374,0.0001133661,0.00008396988,0.0001993474,0.00001562104,0.003050103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.659278,"threshold_uncertainty_score":0.3510644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02210793938368992,"score_gpt":0.2647154058416624,"score_spread":0.2426074664579725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}