{"id":"W2133508153","doi":"10.3945/jn.111.147132","title":"Prebiotic Fiber Increases Hepatic Acetyl CoA Carboxylase Phosphorylation and Suppresses Glucose-Dependent Insulinotropic Polypeptide Secretion More Effectively When Used with Metformin in Obese Rats,","year":2012,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; AMPK; Gastric inhibitory polypeptide; Glucagon-like peptide-1; Metformin; Adiponectin; Chemistry; Acetyl-CoA carboxylase; Enteroendocrine cell; Secretion; Leptin; Protein kinase A; Gut flora; Prebiotic; Insulin; Type 2 diabetes; Insulin resistance; Glucagon; Diabetes mellitus; Hormone; Pyruvate carboxylase; Biology; Medicine; Kinase; Endocrine system; Obesity; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001582012,0.000917466,0.0005682083,0.0006395601,0.0003250634,0.0003117494,0.000277806,0.0004615456,0.00233266],"category_scores_gemma":[0.0002121647,0.0003221766,0.0004233097,0.0002678449,0.000555545,0.0005737304,0.0002409875,0.001431646,0.0002519817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003264644,"about_ca_system_score_gemma":0.0005976115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001702574,"about_ca_topic_score_gemma":0.003539645,"domain_scores_codex":[0.9998801,0.00002152848,0.00001082844,0.00003079778,0.00002297862,0.00003377713],"domain_scores_gemma":[0.9997767,0.00002167639,0.00004610704,0.0000260596,0.00002215449,0.0001073158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01446178,0.0009401005,0.0004121202,0.00009497843,0.00004957138,0.00008928501,0.00002794138,0.00005582062,0.9800779,0.0001056125,0.00009957243,0.003585332],"study_design_scores_gemma":[0.0006687168,0.007314598,0.007959937,0.00001724249,0.0001670154,0.0001308713,0.0000942644,0.0003931907,0.9813396,0.000109522,0.001789649,0.00001537296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965456,0.001098466,0.0007948583,0.0002001774,0.0001333536,0.00003272822,0.0002327761,0.00006753118,0.0008944334],"genre_scores_gemma":[0.9892535,0.001694629,0.00187188,0.0002057491,0.00006967664,0.00008173323,0.0007266299,0.000055306,0.006040887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00233266,"threshold_uncertainty_score":0.0078035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009852287544387309,"score_gpt":0.2393995364327507,"score_spread":0.2295472488883634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}