{"id":"W2133508757","doi":"10.1093/jac/dkq083","title":"Antibacterial activity of guanidinylated neomycin B- and kanamycin A-derived amphiphilic lipid conjugates","year":2010,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Antimicrobial agents and applications","field":"Chemistry","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Kanamycin; Neomycin; Antibacterial activity; Microbiology; Pseudomonas aeruginosa; Staphylococcus epidermidis; Staphylococcus aureus; Chemistry; Antibacterial agent; Biology; Antibiotics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001329954,0.0002707251,0.0001365848,0.00009893324,0.00006582521,0.0001272815,0.00009407159,0.0002062183,0.0005751635],"category_scores_gemma":[0.0001481852,0.00007819093,0.00009682948,0.00009951741,0.0001193889,0.0001708984,0.0001540403,0.0002178053,0.0001510275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001189083,"about_ca_system_score_gemma":0.0001086903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001701224,"about_ca_topic_score_gemma":0.0001873028,"domain_scores_codex":[0.9999284,0.00001760647,0.000009568147,0.00001260906,0.00001937649,0.00001250998],"domain_scores_gemma":[0.9999062,0.00001573204,0.00003349489,0.000007705758,0.00001783211,0.00001894327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006935796,0.000009465398,0.00007346804,0.00002247812,0.000001793667,0.00001189522,0.000007734507,0.00005078312,0.9991941,0.0000181486,0.000004138712,0.0005367821],"study_design_scores_gemma":[0.00001103786,0.0005130535,0.001133253,0.00000373159,0.000008551679,0.00006443869,0.000007593337,0.0002313429,0.9975532,0.000007291307,0.0004638167,0.000002677083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988079,0.0003207394,0.0004975439,0.00001122329,0.000003456173,0.000009771187,0.00003064899,0.000007572402,0.0003111729],"genre_scores_gemma":[0.9977399,0.0003218579,0.00113487,0.00001252091,0.000002130237,0.00001747103,0.0001051638,0.000006051196,0.0006599763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005751635,"threshold_uncertainty_score":0.001924098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007050030868690858,"score_gpt":0.229863421106398,"score_spread":0.2228133902377072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}