{"id":"W2133535272","doi":"10.1158/1078-0432.ccr-12-2117","title":"Sequential Binary Gene Ratio Tests Define a Novel Molecular Diagnostic Strategy for Malignant Pleural Mesothelioma","year":2013,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; U.S. Public Health Service; Vancouver Foundation","keywords":"Mesothelioma; Pleural disease; Computational biology; Medicine; Pathology; Oncology; Biology; Respiratory disease; Internal medicine; Lung","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00105732,0.0006517054,0.0004912791,0.001542797,0.000181493,0.0006293377,0.0005094434,0.0004078012,0.000998802],"category_scores_gemma":[0.002258637,0.0002107472,0.0004063261,0.0005911686,0.0005365417,0.0005371039,0.000452343,0.0004324447,0.0003615802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003739223,"about_ca_system_score_gemma":0.0004279414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002496954,"about_ca_topic_score_gemma":0.0004579956,"domain_scores_codex":[0.9991328,0.0002178684,0.00004992384,0.0002300501,0.0003068174,0.00006260866],"domain_scores_gemma":[0.9992242,0.0003283881,0.00019947,0.00006686997,0.0001227246,0.00005838135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001096156,0.0002462503,0.05745783,0.0003389369,0.00009739048,0.0003137813,0.00007459173,0.005255083,0.8027873,0.001726612,0.0006034875,0.1300025],"study_design_scores_gemma":[0.0001977404,0.003106606,0.1624163,0.00006441616,0.0003820386,0.003263848,0.0002545168,0.1602553,0.6530957,0.00940825,0.007461901,0.00009343402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8261759,0.001611173,0.1662711,0.0006019907,0.0000767147,0.0002924746,0.0009758362,0.001251062,0.002743667],"genre_scores_gemma":[0.8781382,0.0003112443,0.1196957,0.0002786398,0.00004434081,0.0001831625,0.0007715439,0.00005406431,0.0005230549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001542797,"threshold_uncertainty_score":0.00559175,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2551047890606198,"score_gpt":0.5033452066928817,"score_spread":0.248240417632262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}