{"id":"W2133663415","doi":"10.1093/infdis/jis679","title":"Whole Genome Pyrosequencing of Rare Hepatitis C Virus Genotypes Enhances Subtype Classification and Identification of Naturally Occurring Drug Resistance Variants","year":2012,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Hepatitis C virus research","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de Santé Publique du Québec","funders":"U.S. Department of Health and Human Services; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Broad Institute; Biotechnology and Biological Sciences Research Council; Deutsche Forschungsgemeinschaft","keywords":"Genotype; Biology; Pyrosequencing; Genome; Hepatitis C virus; Genetics; Drug resistance; Virology; Identification (biology); DNA sequencing; Virus; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001198515,0.0004311738,0.0005302755,0.0006774311,0.000315319,0.0006172827,0.0003221357,0.0005428137,0.0008520785],"category_scores_gemma":[0.002077575,0.0003099975,0.0004261827,0.0003427422,0.0003188298,0.00026754,0.0005217044,0.0008111065,0.0004676533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002134312,"about_ca_system_score_gemma":0.0003489536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004394547,"about_ca_topic_score_gemma":0.001406723,"domain_scores_codex":[0.999333,0.0001894,0.0000439772,0.0001950477,0.0001603146,0.0000782701],"domain_scores_gemma":[0.9990835,0.0004295011,0.0001383234,0.0001436527,0.0001416766,0.00006332048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000422568,0.000155511,0.01695192,0.00007018816,0.00005265385,0.00009744234,0.0001350059,0.001617302,0.9617898,0.0002396932,0.0001230917,0.01834471],"study_design_scores_gemma":[0.00008254052,0.001264696,0.158506,0.00004614204,0.0002227143,0.002188564,0.0001798141,0.05843161,0.772742,0.001873229,0.004396734,0.00006593765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9699557,0.0002796547,0.02775828,0.00006633974,0.0000144003,0.00007407786,0.0008038392,0.0001263661,0.0009211757],"genre_scores_gemma":[0.9362077,0.0001674132,0.0609028,0.000124498,0.00001233246,0.00006230958,0.001712994,0.00005838707,0.0007516008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001198515,"threshold_uncertainty_score":0.006338418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01755528146881417,"score_gpt":0.2920194140326819,"score_spread":0.2744641325638678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}