{"id":"W2133701384","doi":"10.1016/j.mehy.2007.08.015","title":"Proposing a causal link between thyroid hormone resistance and primary autoimmune hypothyroidism","year":2007,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Thyroid; Autoantibody; Autoimmune thyroiditis; Hormone; Thyroiditis; Endocrinology; Receptor; Medicine; Cytokine; Internal medicine; Immunology; Anti-thyroid autoantibodies; Cytotoxic T cell; Antibody; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002364499,0.0004234768,0.0003735103,0.001723191,0.000714921,0.001503663,0.001596286,0.00405637,0.01491616],"category_scores_gemma":[0.006724251,0.0003082511,0.0007495261,0.0005689695,0.003417307,0.002383483,0.001006861,0.002793216,0.001341451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004772541,"about_ca_system_score_gemma":0.0008483131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002847809,"about_ca_topic_score_gemma":0.0002390791,"domain_scores_codex":[0.9994912,0.0001850652,0.00004669137,0.0001336206,0.00007861557,0.00006477343],"domain_scores_gemma":[0.9943296,0.004082507,0.0006365338,0.0003667963,0.000339993,0.0002446434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.003590856,0.001854135,0.1426309,0.00299981,0.001206714,0.06795292,0.002381831,0.001735184,0.01685483,0.5940492,0.03676912,0.1279745],"study_design_scores_gemma":[0.001751849,0.001159013,0.02242105,0.0004990946,0.001132776,0.05742783,0.002977936,0.006810924,0.008216658,0.8358817,0.06160313,0.0001181305],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.3819224,0.04154913,0.04746993,0.4368165,0.01537956,0.0002955268,0.001011387,0.000559014,0.07499661],"genre_scores_gemma":[0.9492834,0.009176556,0.007859143,0.01643365,0.01055847,0.00006762259,0.0003231778,0.0000159658,0.006282034],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01491616,"threshold_uncertainty_score":0.04989952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01748993085593736,"score_gpt":0.2681025413619421,"score_spread":0.2506126105060048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}