{"id":"W2133766236","doi":"10.1373/clinchem.2004.035071","title":"Analytical Validation of the Tag-It High-Throughput Microsphere-Based Universal Array Genotyping Platform: Application to the Multiplex Detection of a Panel of Thrombophilia-Associated Single-Nucleotide Polymorphisms","year":2004,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Multiplex; Genotyping; SNP genotyping; Single-nucleotide polymorphism; Molecular Inversion Probe; SNP; Genotype; Genetics; Primer (cosmetics); Multiplex polymerase chain reaction; Computational biology; Biology; Polymerase chain reaction; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005541934,0.0001608843,0.0004871131,0.00001832355,0.00008001173,0.000006851709,0.0002389921,0.0002893778,0.00004508423],"category_scores_gemma":[0.000681305,0.0001167381,0.00030452,0.0004657396,0.000275564,0.00004370269,0.00005615087,0.000279552,0.000005245604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001607677,"about_ca_system_score_gemma":0.0002055782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001313422,"about_ca_topic_score_gemma":0.00002388372,"domain_scores_codex":[0.9981348,0.00005223003,0.0009307064,0.0003098273,0.0003747621,0.0001976575],"domain_scores_gemma":[0.9980808,0.0002397401,0.0006752991,0.0005956356,0.000294404,0.0001141487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002076715,0.0007630528,0.004702157,0.00008150002,0.0001339563,3.172176e-7,0.0001103168,0.001056224,0.9920827,0.00009202839,0.00001302962,0.0007570201],"study_design_scores_gemma":[0.002486874,0.0002054184,0.03094709,0.0002029442,0.0003343016,0.000001857557,0.0001590964,0.0009502866,0.9642208,0.0003198706,0.00006528811,0.000106214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846117,0.00001400534,0.01283906,0.001771699,0.0001284555,0.0004546964,0.00002694273,0.00003240702,0.0001209655],"genre_scores_gemma":[0.9986607,0.000004318959,0.0007572733,0.0003412453,0.0001110454,0.000007805207,0.00004638659,0.00002245055,0.0000487391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02786197,"threshold_uncertainty_score":0.4760441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06127903002800464,"score_gpt":0.3031589648810255,"score_spread":0.2418799348530209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}